Cell type specificity of glucocorticoid signaling in the adult mouse hippocampus
EMG Viho, JC Buurstede, JB Berkhout… - Journal of …, 2022 - Wiley Online Library
Glucocorticoid stress hormones are powerful modulators of brain function and can affect
mood and cognitive processes. The hippocampus is a prominent glucocorticoid target and …
mood and cognitive processes. The hippocampus is a prominent glucocorticoid target and …
Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time
MC Morsink, PJ Steenbergen, JB Vos… - Journal of …, 2006 - Wiley Online Library
Several aspects of hippocampal cell function are influenced by adrenal‐secreted
glucocorticoids in a delayed, genomic fashion. Previously, we used Serial Analysis of Gene …
glucocorticoids in a delayed, genomic fashion. Previously, we used Serial Analysis of Gene …
Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites
ICG Weaver, P La Plante, S Weaver, A Parent… - Molecular and cellular …, 2001 - Elsevier
Environmental conditions in early life permanently alter the development of glucocorticoid
receptor gene expression in the hippocampus and hypothalamic–pituitary–adrenal …
receptor gene expression in the hippocampus and hypothalamic–pituitary–adrenal …
Transcriptional glucocorticoid effects in the brain: Finding the relevant target genes
OC Meijer, JC Buurstede, EMG Viho… - Journal of …, 2023 - Wiley Online Library
Glucocorticoids are powerful modulators of brain function. They act via mineralocorticoid
and glucocorticoid receptors (MR and GR). These are best understood as transcription …
and glucocorticoid receptors (MR and GR). These are best understood as transcription …
Mineralo-and glucocorticoid receptor mRNAs are differently regulated by corticosterone in the rat hippocampus and anterior pituitary
ME Hügin-Flores, T Steimer, ML Aubert… - Neuroendocrinology, 2004 - karger.com
In most cell lines and animal tissues, glucocorticoid receptors undergo downregulation after
exposure to corticosterone. However, corticosterone treatment has not shown a consistent …
exposure to corticosterone. However, corticosterone treatment has not shown a consistent …
Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone
H Karst, S Berger, M Turiault… - Proceedings of the …, 2005 - National Acad Sciences
The adrenal hormone corticosterone transcriptionally regulates responsive genes in the
rodent hippocampus through nuclear mineralocorticoid and glucocorticoid receptors. Via …
rodent hippocampus through nuclear mineralocorticoid and glucocorticoid receptors. Via …
Specific regulatory motifs predict glucocorticoid responsiveness of hippocampal gene expression
NA Datson, JAE Polman, RT De Jonge… - …, 2011 - academic.oup.com
The glucocorticoid receptor (GR) is an ubiquitously expressed ligand-activated transcription
factor that mediates effects of cortisol in relation to adaptation to stress. In the brain, GR …
factor that mediates effects of cortisol in relation to adaptation to stress. In the brain, GR …
Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites
Environmental conditions in early life permanently alter the development of glucocorticoid
receptor gene expression in the hippocampus and hypothalamic‐pituitary‐adrenal …
receptor gene expression in the hippocampus and hypothalamic‐pituitary‐adrenal …
Regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in vivo
Glucocorticoid receptors (GRs) are glucocorticoid-activated transcription factors that
modulate expression of a variety of neuronal genes. Appropriate control of GR expression is …
modulate expression of a variety of neuronal genes. Appropriate control of GR expression is …
Development of mRNAs for glucocorticoid and mineralocorticoid receptors in rat hippocampus
MC Bohn, D Dean, S Hussain, R Giuliano - Developmental brain research, 1994 - Elsevier
The hippocampus plays an important role in mediating glucocorticoid effects on the brain.
Glucocorticoids are also implicated in neurogenesis and aged-related neuronal death in the …
Glucocorticoids are also implicated in neurogenesis and aged-related neuronal death in the …