Transcription factors in alkaloid engineering

Y Yamada, F Sato - Biomolecules, 2021 - mdpi.com
Plants produce a large variety of low-molecular-weight and specialized secondary
compounds. Among them, nitrogen-containing alkaloids are the most biologically active and …

Transcription factors in alkaloid biosynthesis

Y Yamada, F Sato - International review of cell and molecular biology, 2013 - Elsevier
Higher plants produce a large variety of low-molecular weight secondary compounds.
Among them, nitrogen-containing alkaloids are the most biologically active and are often …

Alkaloid biosynthesis: metabolism and trafficking

J Ziegler, PJ Facchini - Annu. Rev. Plant Biol., 2008 - annualreviews.org
Alkaloids represent a highly diverse group of compounds that are related only by the
occurrence of a nitrogen atom in a heterocyclic ring. Plants are estimated to produce …

Regulation of alkaloid biosynthesis in plants

PJ Facchini - The alkaloids: chemistry and biology, 2006 - Elsevier
Publisher Summary This chapter focuses on recent advances in the metabolic regulation
involved in the biosynthesis of six groups of alkaloids—benzylisoquinoline (BA) …

Interplay of transcription factors orchestrating the biosynthesis of plant alkaloids

RC Godbole, AA Pable, S Singh, VT Barvkar - 3 Biotech, 2022 - Springer
Plants produce a range of secondary metabolites primarily as defence molecules. A plant
has to invest considerable energy to synthesise alkaloids, and sometimes they are even …

The expanding universe of alkaloid biosynthesis

V De Luca, P Laflamme - Current Opinion in Plant Biology, 2001 - Elsevier
Characterization of many of the major gene families responsible for the generation of central
intermediates and for their decoration, together with the development of large genomics and …

Genome-wide identification of AP2/ERF transcription factor-encoding genes in California poppy (Eschscholzia californica) and their expression profiles in response to …

Y Yamada, S Nishida, N Shitan, F Sato - Scientific reports, 2020 - nature.com
With respect to the biosynthesis of plant alkaloids, that of benzylisoquinoline alkaloids (BIAs)
has been the most investigated at the molecular level. Previous investigations have shown …

Implementation of functional genomics for gene discovery in alkaloid producing plants

A Goossens, H Rischer - Phytochemistry Reviews, 2007 - Springer
Two centuries after the discovery of the first alkaloids, many enzymes involved in plant
alkaloid biosynthesis have been identified. Nevertheless, the biosynthetic pathways for most …

Engineering plant alkaloid biosynthetic pathways: progress and prospects

TM Kutchan, S Frick, M Weid - … in Plant Biochemistry and Molecular Biology, 2008 - Elsevier
With the successful application of molecular genetic methods to the plant alkaloid field, we
now have sophisticated tools at our disposal to study regulation of enzymatic biosynthesis …

Biosynthesis and regulation of alkaloids

G Guirimand, V Courdavault, B St-Pierre… - … Perspectives: Volume 2, 2010 - Springer
Alkaloids constitute a very chemically diverse group of plant natural products. These
molecules, of which about 12,000 have been identified, share the common presence of a …