We investigated the effects of treatment with tranilast on vascular and metabolic dysfunction
induced by a high-fat emulsion intragastric administration. Wistar rats were randomized to …

In diabetes mellitus (DM), high glucose can result in endothelial cell injury, and then lead to
diabetic vascular complications. Gastrodin, as the mainly components of Chinese traditional …

Rationale Hypertension in obesity has become a major threat for public health. Omentin-1, a
novel adipokine, is down-regulated in obesity. Tetrahydroxystilbene glycoside (TSG) is the …

Gossypetin (GTIN), known as 3, 5, 7, 8, 3′, 4′-hexahydroxyflavone, has been
demonstrated to exert anti-atherosclerotic potential against apoptotic injury in oxidized low …

The initiation of atherosclerosis (AS) induced by dyslipidemia is accompanied by endothelial
dysfunction, including decreased healing ability and increased recruitment of monocytes …

Geraniin, an ellagitannin, has shown a potent blood pressure-lowering effect in vivo.
Therefore, this study aims to further characterize the ability of geraniin to attenuate …

Endothelial dysfunction occurs in obese patients and high-fat diet (HFD) fed experimental
animals. While geraniol has been reported to ameliorate inflammation and oxidative stress …

Background Insulin resistance in endothelial cells contributes to the development of
cardiovascular disease in type 2 diabetes mellitus (T2DM). Therefore, there are great …

Endothelial dysfunction is a common complication of diabetes that mainly stems from
increased reactive oxygen species, which makes antioxidants of great benefit. Resveratrol …

Abstract High-fat diet (HFD)-induced obesity leads endothelial dysfunction and contributes
to cardiovascular diseases. Palmitic acid (PA), a free fatty acid, is the main component of …