Background Developmental programming of the embryo is controlled by genetic information
but also dictated by epigenetic information contained in spermatozoa. Lifestyle and …

Epigenetic inheritance and its underlying molecular mechanisms are among the most
intriguing areas of current biological and medical research. To date, studies have shown that …

In the last 40 years, male reproductive health—which is very sensitive to both environmental
exposure and metabolic status—has deteriorated and the poor sperm quality observed has …

The past decade has seen a tremendous increase in interest and progress in the field of
sperm epigenetics. Studies have shown that chromatin regulation during male germline …

Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …

Recent work in the field of male fertility has yielded significant increases in our
understanding of the sperm epigenome and its potential role in embryonic development …

Male germ cells require multiple epigenetic reprogramming events during their lifespan to
achieve reproductive capacity. An emerging body of compelling data demonstrates that …

The mammalian sperm contains a highly unique and specialized epigenetic landscape that
offers a great degree of interesting research opportunities. One key discriminating feature of …

During fertilization, spermatozoa contribute genetic and epigenetic factors that affect early
embryogenesis. Genetic factors include a haploid genome with intact coding regions and …

Recent advances, including the human genome project and numerous studies of cancer
and other diseases, have shown that the genetic code is not simply limited to the sequence …