Background Many people experience withdrawal symptoms when they attempt to stop
antidepressants. Withdrawal symptoms are readily misconstrued for relapse or ongoing …

Background Stopping long-term (> 12 months) antidepressant use can be difficult due to
unpleasant withdrawal symptoms. Many people do not recognise withdrawal symptoms or …

The body initially intended to publish a full update in January 2018, but chose to delay and
re-consult on the plans after experts raised concerns at what they viewed as “significant …

Background Around one in ten adults take antidepressants for depression in England, and
their long-term use is increasing. Some need them to prevent relapse, but 30–50% could …

Background: There has been a steady increase in the number of primary care patients
receiving long-term maintenance antidepressant treatment, despite limited evidence of a …

Background Inappropriate use of antidepressants (AD), defined as either continuation in the
absence of a proper indication or continuation despite the lack of therapeutic efficacy …

PURPOSE We aimed to determine the effectiveness of interventions to manage
antidepressant discontinuation, and the outcomes for patients. METHODS We conducted a …

This review considers evidence for the efficacy of pharmacotherapy among primary care
patients with depressive disorders and reviews knowledge regarding the effectiveness of …

Background: Tapering and discontinuing antidepressants are important aspects of the
management of patients with depression and should therefore be considered in clinical …

Background Practices vary in the duration of newly initiated antidepressant treatment, even
after adjusting for patient characteristics. It was hypothesised that this may be because of …