Efficacy of adipose-derived stromal vascular fraction cells in the management of chronic ulcers: a randomized clinical trial

E Tanios, TM Ahmed, EA Shafik, MF Sherif… - Regenerative …, 2021 - Taylor & Francis
Background: Cell therapy is a promising method for improving healing in chronic ulcers
through delivery of isolated adipose-derived stromal vascular fraction. Objectives: This study …

Therapy with autologous adipose-derived regenerative cells for the care of chronic ulcer of lower limbs in patients with peripheral arterial disease

G Marino, M Moraci, E Armenia, C Orabona… - Journal of Surgical …, 2013 - Elsevier
Background An ulcer is a trophic lesion with loss of tissue that often has a multifactorial
genesis. It typically diverges from the physiologic processes of regeneration because it …

Adipose-derived stromal cells for chronic wounds: scientific evidence and roadmap toward clinical practice

NC Brembilla, H Vuagnat, WH Boehncke… - Stem Cells …, 2023 - academic.oup.com
Chronic wounds, ie, non-healing ulcers, have a prevalence of~ 1% in the general
population. Chronic wounds strongly affect the quality of life and generate considerable …

Autologous adipose-derived stem cells: basic science, technique, and rationale for application in ulcer and wound healing

I Zollino, M Zuolo, S Gianesini, M Pedriali… - …, 2017 - journals.sagepub.com
Objectives The present review represents a translational boundary between basic research
and surgery, particularly focusing on the promising application of adipose-derived stem cells …

A phase II randomized clinical trial for the treatment of recalcitrant chronic leg ulcers using centrifuged adipose tissue containing progenitor cells

I Zollino, D Campioni, MG Sibilla, M Tessari… - Cytotherapy, 2019 - Elsevier
Background aims Preclinical and observational reports indicate that adipose tissue (AT) is a
safe and promising tool to treat non-healing venous leg ulcers (VLUs). Methods From an …

Adipose-derived stem cells for treatment of chronic ulcers: current status

JS Holm, NM Toyserkani, JA Sorensen - Stem cell research & therapy, 2018 - Springer
Chronic ulcers remain a difficult challenge in healthcare systems. While treatment options
are limited, stem cells may be a novel alternative. Adipose-derived stem cells (ADSC) have …

Adipose-derived stem cells for treatment of chronic cutaneous ulcers in patients with critical limb ischemia: a pilot study

E Raposio, N Bertozzi, E Grignaffini… - European Journal of …, 2018 - Springer
Background Therapeutic approaches based on stem cells have recently been introduced to
treat chronic ulcers, with good results. The aim of this study was to evaluate whether the …

Autotransplantation of the adipose tissue-derived mesenchymal stromal cells in therapy of venous stasis ulcers

L Masłowski, M Paprocka… - Archivum Immunologiae …, 2020 - Springer
Adipose tissue is a reliable source of mesenchymal stromal cells (MSC) for use in
regenerative medicine. The aim of this pilot study was to describe the method, and assess …

Micronized cellular adipose matrix as a therapeutic injectable for diabetic ulcer

J Feng, K Doi, S Kuno, K Mineda, H Kato… - Regenerative …, 2015 - Taylor & Francis
Background: Despite the clinical potential of adipose-derived stem/stromal cells (ASCs),
there are some clinical difficulties due to the regulation of cell therapies. Materials & …

Adipose tissue-derived stromal cells for wound healing

P Goodarzi, S Alavi-Moghadam, M Sarvari… - Cell Biology and …, 2018 - Springer
Skin as the outer layer covers the body. Wounds can affect this vital organ negatively and
disrupt its functions. Wound healing as a biological process is initiated immediately after an …