The natural process of human immunodeficiency virus type 1 (HIV-1) infection is
characterized by high viral load, immune cell exhaustion, and immunodeficiency, which …

Although antiretroviral therapy (ART) has drastically changed the lives of people living with
human immunodeficiency virus-1 (HIV-1), long-term treatment has been associated with a …

HIV-1 infection is a major public health problem and an important cause of death among
adults. In light of innate immune system being the first, rapid and nonspecific response, this …

The natural course of human immunodeficiency virus (HIV) infection is characterized by high
viral load, depletion of immune cells, and immunodeficiency, ultimately leading to acquired …

Host immune components play both beneficial and pathogenic roles in human
immunodeficiency virus type 1 (HIV‐1) infection. During the initial stage of viral infection, a …

From the publication of the first AIDS issue onwards, major advances have been made in the
field of innate immunity during HIV infection. Innate immunity can be defined as the first and …

Accumulating data generated from persons who naturally control HIV without the need for
antiretroviral treatment has led to significant insights into the possible mechanisms of …

Following the success of HIV-1 antiviral treatment that maintains undetectable levels of viral
replication and lack of clinical progression, the design of an HIV-1 cure for patients became …

Elite controllers (EC) represent a small subset of HIV-1-infected people that spontaneously
control viral replication. However, natural virological suppression and absence of immune …

The exceptional group of ECs has been of great help, and will continue to provide
invaluable insight with regard to reach a potential functional cure of HIV. However, there is …