Globally, over 500 million people are chronically infected with the hepatitis B virus (HBV) or
hepatitis C virus (HCV). These chronic infections cause liver inflammation, and may result in …

Globally, hepatitis B virus (HBV) infection and its related liver diseases account for 780,000
deaths every year. Outcomes of HBV infection depend on the interaction between the virus …

Kupffer cells, the resident liver macrophages have long been considered as mostly
scavenger cells responsible for removing particulate material from the portal circulation …

Kupffer cells, the largest tissue resident macrophage population, are key for the
maintenance of liver integrity and its restoration after injury and infections, as well as the …

Kupffer cells (KC) constitute 80–90% of the tissue macrophages present in the body. They
reside within the lumen of the liver sinusoids, and are therefore constantly exposed to gut …

Kupffer cells (KCs) are widely considered important contributors to liver injury during viral
hepatitis due to their pro-inflammatory activity. Herein we utilized hepatitis B virus (HBV) …

Macrophages represent a key cellular component of the liver, and are essential for
maintaining tissue homeostasis and ensuring rapid responses to hepatic injury. Our …

Kupffer cells (KCs) are highly abundant, intravascular, liver-resident macrophages known for
their scavenger and phagocytic functions. KCs can also present antigens to CD8+ T cells …

Background. Based on their localization, Kupffer cells (KCs) likely interact with hepatitis B
virus (HBV). However, the role of KCs in inducing immunity toward HBV is poorly …

Kupffer cells are a critical component of the mononuclear phagocytic system and are central
to both the hepatic and systemic response to pathogens. Kupffer cells are reemerging as …