Liver fibrogenesis is a dynamic and highly integrated molecular, tissue and cellular process,
potentially reversible, that drives the progression of chronic liver diseases (CLD) towards …

The progression of chronic liver diseases (CLD), irrespective of etiology, involves chronic
parenchymal injury, persistent activation of inflammatory response as well as sustained …

Hepatic fibrosis represents the wound‐healing response process of the liver to chronic
injury, independently from aetiology. Advanced liver fibrosis results in cirrhosis that can lead …

The most common cause of liver failure is cirrhosis, due to progressive liver fibrosis and
other architectural changes in the liver. Fibrosis occurs after liver injury or stress and results …

Fibrotic progression of chronic liver diseases of different aetiology to the common advanced-
stage of cirrhosis can be envisaged as a dynamic and highly integrated cellular response to …

The pathophysiology of liver injury has attracted the interest of experimentalists and
clinicians over many centuries. With the discovery of liver‐specific pericytes–formerly called …

Liver fibrosis results from dysregulation of normal wound healing, inflammation, activation of
myofibroblasts, and deposition of extracellular matrix (ECM). Chronic liver injury causes …

There have been considerable recent advances towards a better understanding of the
complex cellular and molecular network underlying liver fibrogenesis. Recent data indicate …

In any chronic liver disease (CLDs), whatever the aetiology, reiteration of liver injury results
in persisting inflammation and progressive fibrogenesis, with chronic activation of the wound …

Multiple etiologies of liver disease lead to liver fibrosis through integrated signaling networks
that regulate the deposition of extracellular matrix. This cascade of responses drives the …