[HTML][HTML] Lipid droplet biogenesis and functions in health and disease

A Zadoorian, X Du, H Yang - Nature Reviews Endocrinology, 2023 - nature.com
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Balancing the fat: lipid droplets and human disease

N Krahmer, RV Farese Jr, TC Walther - EMBO molecular medicine, 2013 - embopress.org
Lipid droplets (LDs) are dynamic, cytosolic lipid‐storage organelles found in nearly all cell
types. Too many or too few LDs during excess or deficient fat storage lead to many different …

Lipid droplets and cellular lipid metabolism

TC Walther, RV Farese Jr - Annual review of biochemistry, 2012 - annualreviews.org
Among organelles, lipid droplets (LDs) uniquely constitute a hydrophobic phase in the
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …

The why, when and how of lipid droplet diversity

AR Thiam, M Beller - Journal of cell science, 2017 - journals.biologists.com
Lipid droplets are the universal cellular organelles for the transient or long-term storage of
lipids. The number, size and composition of lipid droplets vary greatly within cells in a …

Lipid droplets: formation to breakdown

A Meyers, TM Weiskittel, P Dalhaimer - Lipids, 2017 - Springer
One of the most exciting areas of cell biology during the last decade has been the study of
lipid droplets. Lipid droplets allow cells to store non-polar molecules such as neutral lipids in …

Deciphering the role of lipid droplets in cardiovascular disease: a report from the 2017 national heart, lung, and blood institute workshop

IJ Goldberg, K Reue, NA Abumrad, PE Bickel… - Circulation, 2018 - Am Heart Assoc
Lipid droplets (LDs) are distinct and dynamic organelles that affect the health of cells and
organs. Much progress has been made in understanding how these structures are formed …

Dynamics and functions of lipid droplets

JA Olzmann, P Carvalho - Nature reviews Molecular cell biology, 2019 - nature.com
Lipid droplets are storage organelles at the centre of lipid and energy homeostasis. They
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …

[HTML][HTML] Lipid droplets finally get a little RESPECT

RV Farese, TC Walther - Cell, 2009 - cell.com
Long underappreciated as important cellular organelles, lipid droplets are finally being
recognized as dynamic structures with a complex and interesting biology. In light of this …

[HTML][HTML] Lipid droplet proteins and metabolic diseases

S Xu, X Zhang, P Liu - Biochimica et Biophysica Acta (BBA)-Molecular …, 2018 - Elsevier
Lipid droplets (LDs) are ubiquitous cellular organelles for lipid storage which are composed
of a neutral lipid core bounded by a protein decorated phospholipid monolayer. Although …

[HTML][HTML] Lipid droplets in cancer: guardians of fat in a stressful world

T Petan, E Jarc, M Jusović - Molecules, 2018 - mdpi.com
Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to …