[HTML][HTML] Lipid droplet biogenesis and functions in health and disease
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …
Balancing the fat: lipid droplets and human disease
Lipid droplets (LDs) are dynamic, cytosolic lipid‐storage organelles found in nearly all cell
types. Too many or too few LDs during excess or deficient fat storage lead to many different …
types. Too many or too few LDs during excess or deficient fat storage lead to many different …
Lipid droplets and cellular lipid metabolism
TC Walther, RV Farese Jr - Annual review of biochemistry, 2012 - annualreviews.org
Among organelles, lipid droplets (LDs) uniquely constitute a hydrophobic phase in the
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …
The why, when and how of lipid droplet diversity
Lipid droplets are the universal cellular organelles for the transient or long-term storage of
lipids. The number, size and composition of lipid droplets vary greatly within cells in a …
lipids. The number, size and composition of lipid droplets vary greatly within cells in a …
Lipid droplets: formation to breakdown
A Meyers, TM Weiskittel, P Dalhaimer - Lipids, 2017 - Springer
One of the most exciting areas of cell biology during the last decade has been the study of
lipid droplets. Lipid droplets allow cells to store non-polar molecules such as neutral lipids in …
lipid droplets. Lipid droplets allow cells to store non-polar molecules such as neutral lipids in …
Deciphering the role of lipid droplets in cardiovascular disease: a report from the 2017 national heart, lung, and blood institute workshop
IJ Goldberg, K Reue, NA Abumrad, PE Bickel… - Circulation, 2018 - Am Heart Assoc
Lipid droplets (LDs) are distinct and dynamic organelles that affect the health of cells and
organs. Much progress has been made in understanding how these structures are formed …
organs. Much progress has been made in understanding how these structures are formed …
Dynamics and functions of lipid droplets
JA Olzmann, P Carvalho - Nature reviews Molecular cell biology, 2019 - nature.com
Lipid droplets are storage organelles at the centre of lipid and energy homeostasis. They
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …
[HTML][HTML] Lipid droplets finally get a little RESPECT
RV Farese, TC Walther - Cell, 2009 - cell.com
Long underappreciated as important cellular organelles, lipid droplets are finally being
recognized as dynamic structures with a complex and interesting biology. In light of this …
recognized as dynamic structures with a complex and interesting biology. In light of this …
[HTML][HTML] Lipid droplet proteins and metabolic diseases
Lipid droplets (LDs) are ubiquitous cellular organelles for lipid storage which are composed
of a neutral lipid core bounded by a protein decorated phospholipid monolayer. Although …
of a neutral lipid core bounded by a protein decorated phospholipid monolayer. Although …
[HTML][HTML] Lipid droplets in cancer: guardians of fat in a stressful world
T Petan, E Jarc, M Jusović - Molecules, 2018 - mdpi.com
Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to …
Their survival during severe nutrient and oxidative stress depends on their capacity to …