Background Small airways dysfunction (SAD) is well recognised in asthma, yet its role in the
severity and control of asthma is unclear. This study aimed to assess which combination of …

Background Although small airway disease is a feature of asthma, its association with
relevant asthma outcomes remains unclear. The ATLANTIS study was designed to identify …

Background Small airways dysfunction and inflammation contribute significantly to the
clinical impact of asthma, yet conventional methods of assessing airways function in the …

Background Little is known about the role of small airway dysfunction (SAD) and its complex
relation with asthma control and physical activity (PA). Objective To investigate the …

The clinical relevance of the small airways in persistent asthma has been gaining greater
recognition in recent years [ 1]. Studies have shown that a significant proportion of …

The small airways in the distal lung have been called the quiet zone because they are
difficult to assess and treat in patients with asthma who have disproportionate impairment of …

Traditionally, asthma has been considered a disease that predominantly involves the large
airways. Today, this concept is being challenged, and increasing evidence has become …

Background The involvement of small airways has recently gained greater recognition in
asthma. Impulse oscillometry (IOS) is a simple and noninvasive method based on the forced …

BACKGROUND: Whether small airways dysfunction persists in patients with asthma
receiving standard community treatment is unknown. Impulse oscillometry (IOS) is a …

The definition of asthma has evolved from that of an episodic disease characterized by
reversible airways constriction to a chronic inflammatory disease of the airways, with at least …