Leveraging physiology for precision drug delivery

W Sun, Q Hu, W Ji, G Wright, Z Gu - Physiological reviews, 2017 - journals.physiology.org
Physiological characteristics of diseases bring about both challenges and opportunities for
targeted drug delivery. Various drug delivery platforms have been devised ranging from …

Applications of stimuli-responsive nanoscale drug delivery systems in translational research

M Gu, X Wang, TB Toh, EKH Chow - Drug Discovery Today, 2018 - Elsevier
Highlights•Nanomedicine is a promising strategy for target-specific delivery of
therapeutics.•Stimuli-responsive nanocarriers enhance tissue specificity.•Advances in …

Advances and challenges of nanotechnology-based drug delivery systems

W Jiang, BYS Kim, JT Rutka… - Expert opinion on drug …, 2007 - Taylor & Francis
The ability to deliver highly efficient therapeutic compounds specifically to diseased sites is
crucial for effectively treating all human illnesses. Unfortunately, conventional therapeutic …

[HTML][HTML] Biologics, theranostics, and personalized medicine in drug delivery systems

M Puccetti, M Pariano, A Schoubben… - Pharmacological …, 2024 - Elsevier
The progress in human disease treatment can be greatly advanced through the
implementation of nanomedicine. This approach involves targeted and cell-specific therapy …

Nanoscale drug delivery systems for controllable drug behaviors by multi-stage barrier penetration

J Wang, Q Ni, Y Wang, Y Zhang, H He, D Gao… - Journal of Controlled …, 2021 - Elsevier
Due to the poor physicochemical properties of drugs and multi-stage biological barriers in
vivo, drugs at action site cannot reach up to sufficient concentration to acquire expected …

[HTML][HTML] Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …

Nanostructure-mediated drug delivery

GA Hughes - Nanomedicine: nanotechnology, biology and medicine, 2005 - Elsevier
Nanotechnology is expected to have an impact on all industries including semiconductors,
manufacturing, and biotechnology. Tools that provide the capability to characterize and …

[PDF][PDF] Designing polymeric nanoparticles for targeted drug delivery system

II Muhamad12, S Selvakumaran, NAM Lazim - Nanomed, 2014 - researchgate.net
New opportunities to prevent and to treat diseases are by emerging the understanding of
disease pathways. The intrinsic limitations of therapeutic biomacromolecules, such as …

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers

Z Zhao, A Ukidve, V Krishnan, S Mitragotri - Advanced drug delivery …, 2019 - Elsevier
Over the years, a plethora of materials–natural and synthetic–have been engineered at a
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …

Nano-enabled delivery of diverse payloads across complex biological barriers

KA Ross, TM Brenza, AM Binnebose, Y Phanse… - Journal of controlled …, 2015 - Elsevier
Complex biological barriers are major obstacles for preventing and treating disease.
Nanocarriers are designed to overcome such obstacles by enhancing drug delivery through …