The food and drug addiction epidemic: targeting dopamine homeostasis
Obesity is damaging the lives of more than 300 million people worldwide and maintaining a
healthy weight using popular weight loss tactics remains a very difficult undertaking …
healthy weight using popular weight loss tactics remains a very difficult undertaking …
[HTML][HTML] Could dopamine agonists aid in drug development for anorexia nervosa?
GKW Frank - Frontiers in nutrition, 2014 - frontiersin.org
Anorexia nervosa is a severe psychiatric disorder most commonly starting during the
teenage-years and associated with food refusal and low body weight. Typically there is a …
teenage-years and associated with food refusal and low body weight. Typically there is a …
The dopamine motive system: implications for drug and food addiction
Behaviours such as eating, copulating, defending oneself or taking addictive drugs begin
with a motivation to initiate the behaviour. Both this motivational drive and the behaviours …
with a motivation to initiate the behaviour. Both this motivational drive and the behaviours …
You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct-and indirect-acting dopamine …
The important role of dopamine (DA) in mediating feeding behavior and the positive
reinforcing effects of some drugs is well recognized. Less widely studied is how feeding …
reinforcing effects of some drugs is well recognized. Less widely studied is how feeding …
Dopamine and diet-induced obesity
AG DiFeliceantonio, DM Small - Nature Neuroscience, 2019 - nature.com
In 2010, Johnson and Kenny provided conclusive evidence that extended access to a
Western-style diet promotes addictive-like behavior in rats by downregulating D2 receptors …
Western-style diet promotes addictive-like behavior in rats by downregulating D2 receptors …
A shared molecular and genetic basis for food and drug addiction: overcoming hypodopaminergic trait/state by incorporating dopamine agonistic therapy in psychiatry
MS Gold, RD Badgaiyan, K Blum - Psychiatric Clinics, 2015 - psych.theclinics.com
How we feel when we are starving or miss a meal, or two, may be linked to the brain's
complex role in controlling appetite. This understanding may be crucial in efforts to develop …
complex role in controlling appetite. This understanding may be crucial in efforts to develop …
[HTML][HTML] Striatal dopamine links gastrointestinal rerouting to altered sweet appetite
Reductions in calorie intake contribute significantly to the positive outcome of bariatric
surgeries. However, the physiological mechanisms linking the rerouting of the …
surgeries. However, the physiological mechanisms linking the rerouting of the …
Pharmacological interventions for obesity: current and future targets
ME Bocarsly - Current addiction reports, 2018 - Springer
Abstract Purpose of Review Obesity in the USA has been on a constant rise since the Center
for Disease Control and Prevention (CDC) began tracking it over 50 years ago. Despite …
for Disease Control and Prevention (CDC) began tracking it over 50 years ago. Despite …
[HTML][HTML] Dopamine signaling in food addiction: role of dopamine D2 receptors
JH Baik - BMB reports, 2013 - ncbi.nlm.nih.gov
Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic
dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are …
dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are …
Mesolimbic dopamine and its neuromodulators in obesity and binge eating
L Naef, KA Pitman, SL Borgland - CNS spectrums, 2015 - cambridge.org
Obesity has reached epidemic prevalence, and much research has focused on homeostatic
and nonhomeostatic mechanisms underlying overconsumption of food. Mesocorticolimbic …
and nonhomeostatic mechanisms underlying overconsumption of food. Mesocorticolimbic …