Small interfering RNA (siRNA) enables efficient target gene silencing by employing a RNA
interference (RNAi) mechanism, which can compromise gene expression and regulate gene …

Since the revolutionary discovery of RNA interference (RNAi), a remarkable progress has
been achieved in understanding and harnessing gene silencing mechanism; especially in …

Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to
become an essential approach in treating a variety of infectious, hemato-oncological …

ABSTRACT RNA interference (RNAi) is an ancient biological mechanism used to defend
against external invasion. It theoretically can silence any disease-related genes in a …

The highly specific induction of RNA interference-mediated gene knockdown, based on the
direct application of small interfering RNAs (siRNAs), opens novel avenues towards …

More than two decades after the natural gene-silencing mechanism of RNA interference was
elucidated, small interfering RNA (siRNA)-based therapeutics have finally broken into the …

RNA interference (RNAi) is a post-transcriptional gene-silencing mechanism that involves
the degradation of messenger RNA in a highly sequence-specific manner. Double-stranded …

Through a mechanism known as RNA interference (RNAi), small interfering RNA (siRNA)
molecules can target complementary mRNA strands for degradation, thus specifically …

Gene silencing by siRNA (short interfering RNA) is a still developing field in biology and has
evolved as a novel post-transcriptional gene silencing strategy with therapeutic potential …

RNA interference (RNAi) was intensively studied in the past decades due to its potential in
therapy of diseases. The target specificity and universal treatment spectrum endowed siRNA …