Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …

This article provides a comprehensive overview of the pathology of multiple sclerosis (MS),
including recent insights into its molecular neuropathology and immunology. It shows that all …

The autoimmune model of multiple sclerosis (MS) pathogenesis provided for many years a
useful but incomplete conceptual framework for understanding the complex array of factors …

Multiple sclerosis, the clinical features and pathological correlate for which were first
described by Charcot, is a chronic neuroinflammatory disease with unknown etiology and …

Multiple sclerosis (MS) is defined as a chronic inflammatory disease of the central nervous
system, which leads to focal inflammatory demyelinated lesions with secondary …

Multiple sclerosis (MS) arises in people who have a genetic susceptibility to environmental
factors and events, which ultimately trigger the disease. It is thought that peripheral immune …

The very simplistic view that inflammation in multiple sclerosis (MS) is tout court detrimental
has to be profoundly reconsidered. Experimental evidence strongly supports the concept …

The focus of multiple sclerosis (MS) research has been on attempts to identify the specific
pathogenic mechanism responsible for producing the multifocal central nervous system …

Pathological examination of the affected human tissue is key to understanding the possible
mechanisms operating in the disease. In multiple sclerosis (MS), studies of central nervous …

Multiple sclerosis (MS) is an autoimmune central nervous system (CNS) demyelinating
disease that causes relapsing and chronic neurologic impairment. Recent observations …