Two venom proteins, a procoagulant ecarin, to rapidly promote blood clot formation, and an
antifibrinolytic textilinin, to prevent blood clot breakdown were recombinantly produced. The …

Uncontrolled bleeding from traumatic injury remains the second leading cause of death that
accounts for 30–40% mortality in a civilian setting and 90% mortality in a military setting …

In this chapter, PicEcarin prepared in Chapter 4 was mixed with recombinant textilinin,
producing snake venom hydrogel wound sealant (Venom gel). Venom gel showed no …

The snake venom protease ecarin from Echis carinatus was expressed in stable transfected
CHO-S cells grown in animal component free cell culture medium. Recombinant ecarin (r …

Snake venoms are mixtures of numerous proteinacious components that exert diverse
functional activities on a variety of physiological targets. Because the toxic constituents …

Snake venoms are attractive for drug discovery and development, with a number of
therapeutics derived from snake venom either in clinical use or in development …

Snake venoms represent a cocktail of thousands of diverse molecules, mainly proteins
accounting for up to 95% of venom's dry weight. These proteins are mainly enzymes such as …

In studies of blood coagulation and the vascular system, snake venom toxins have been
indispensable in elucidating the complex physiological mechanisms that govern coagulation …

The Potential of Snake Venoms as Coagulation Agent for Hemorrhagic Trauma: A Review
Page 1 39 | Revelation and Science / Vol. 13, No. 01 (1444H/2023) Revelation and Science …

Snake venoms are complex mixtures containing many different biologically active proteins
and peptides. A number of these proteins act on components of the haemostatic system in …