The fibrogenic niche in kidney fibrosis: components and mechanisms
Kidney fibrosis, characterized by excessive deposition of extracellular matrix (ECM) that
leads to tissue scarring, is the final common outcome of a wide variety of chronic kidney …
leads to tissue scarring, is the final common outcome of a wide variety of chronic kidney …
[HTML][HTML] Defining therapeutic targets for renal fibrosis: Exploiting the biology of pathogenesis
H Yan, J Xu, Z Xu, B Yang, P Luo, Q He - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Renal fibrosis is a failed wound-healing process of the kidney tissue after chronic, sustained
injury, which is a common pathway and pathological marker of virtually every type of chronic …
injury, which is a common pathway and pathological marker of virtually every type of chronic …
Kidney fibrosis: from mechanisms to therapeutic medicines
R Huang, P Fu, L Ma - Signal Transduction and Targeted Therapy, 2023 - nature.com
Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …
Cellular and molecular mechanisms of kidney fibrosis
Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …
injury or maladaptive repair. It is considered as the underlying pathological process of …
The origin of renal fibroblasts/myofibroblasts and the signals that trigger fibrosis
YBY Sun, X Qu, G Caruana, J Li - Differentiation, 2016 - Elsevier
Renal fibrosis is a common characteristic of chronic kidney disease (CKD). Aberrant and
excessive depositions of extracellular matrix (ECM) proteins in both glomeruli and interstitial …
excessive depositions of extracellular matrix (ECM) proteins in both glomeruli and interstitial …
What can target kidney fibrosis?
IA Leaf, JS Duffield - Nephrology Dialysis Transplantation, 2017 - academic.oup.com
Fibrosis, a characteristic of all chronic kidney diseases, is now recognized to be an
independent predictor of disease progression. Deposition of pathological matrix in the walls …
independent predictor of disease progression. Deposition of pathological matrix in the walls …
Extracellular matrix in kidney fibrosis: more than just a scaffold
Kidney fibrosis is the common histological end-point of progressive, chronic kidney diseases
(CKDs) regardless of the underlying etiology. The hallmark of renal fibrosis, similar to all …
(CKDs) regardless of the underlying etiology. The hallmark of renal fibrosis, similar to all …
Renal fibrosis: novel insights into mechanisms and therapeutic targets
Renal fibrosis is the common end point of virtually all progressive kidney diseases. Renal
fibrosis should not be viewed as a simple and uniform'scar', but rather as a dynamic system …
fibrosis should not be viewed as a simple and uniform'scar', but rather as a dynamic system …
Cellular and molecular mechanisms in kidney fibrosis
JS Duffield - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
Fibrosis is a characteristic feature of all forms of chronic kidney disease. Deposition of
pathological matrix in the interstitial space and within the walls of glomerular capillaries as …
pathological matrix in the interstitial space and within the walls of glomerular capillaries as …
Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis
S Rayego-Mateos, S Campillo… - Clinical …, 2021 - portlandpress.com
Chronic kidney disease (CKD) is characterized by pathological accumulation of extracellular
matrix (ECM) proteins in renal structures. Tubulointerstitial fibrosis is observed in glomerular …
matrix (ECM) proteins in renal structures. Tubulointerstitial fibrosis is observed in glomerular …