Abstract LOX‐1 (lectin‐like oxidized low‐density lipoprotein receptor‐1; also known as
OLR1) is the dominant receptor that recognizes and internalizes oxidized low‐density …

Oxidatively modified low-density lipoprotein (oxLDL) is implicated in the pathogenesis of
atherosclerosis. Endothelial dysfunction is the initial change in the vascular wall that induces …

Abstract Purpose of Review In any case, in proatherogenic conditions, LOX-1 is uniquely
upregulated in vascular cells and mediates the entire atherogenic process from LDL …

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), one of the scavenger
receptors for oxidized low-density lipoprotein cholesterol (ox-LDL), plays a crucial role in the …

Lectin-like oxidized LDL (oxLDL) receptor-1 (LOX-1, also known as OLR-1), is a class E
scavenger receptor that mediates the uptake of oxLDL by vascular cells. LOX-1 is involved …

Atherosclerosis, the underlying cause of cardiovascular disease (CVD), is a worldwide
cause of morbidity and mortality. Reducing ApoB-containing lipoproteins—chiefly, LDL (low …

Abstract LOX-1, a lectin-like 52-kD receptor for oxidized low-density lipoproteins (ox-LDL), is
present primarily on endothelial cells. This receptor is upregulated by ox-LDL itself and by …

LOX-1 is an endothelial receptor for oxidized low-density lipoprotein (oxLDL), a key
molecule in the pathogenesis of atherosclerosis. The basal expression of LOX-1 is low but …

In healthy arteries, expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-
1) is almost undetectable. However, in proatherogenic conditions, LOX-1 is markedly …

LOX‐1 is a scavenger receptor that functions as the primary receptor for oxidized low‐
density lipoprotein (OxLDL) in endothelial cells. The binding of OxLDL to LOX‐1 is believed …