Nanotechnology-based approaches for targeting and delivery of drugs via Hexakis (m-PE) macrocycles

S Pasban, H Raissi - Scientific reports, 2021 - nature.com
Abstract Hexakis (m-phenylene ethynylene)(m-PE) macrocycles, with aromatic backbones
and multiple hydrogen-bonding side chains, had a very high propensity to self-assemble via …

New insights into Hexakis macrocycles as a novel nano-carrier for highly potent anti-cancer treatment: A new challenge in drug delivery

S Pasban, H Raissi - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
The purpose of this study is to design and evaluate a new tubular assembly structure of
Hexakis (m-phenylene ethynylene)(m-PE) macrocycles and to explore its potential …

Cation-pi interaction: A strategy for enhancing the performance of graphene-based drug delivery systems

A Zaboli, H Raissi, F Farzad, H Hashemzadeh… - Inorganic Chemistry …, 2022 - Elsevier
To enhance the therapeutic properties of doxorubicin (DOX), a series of novel drug delivery
systems (DDS) based on the cation-π complex is designed. The effect of Li, Na, K, Be, and …

PNIPAM/Hexakis as a thermosensitive drug delivery system for biomedical and pharmaceutical applications

S Pasban, H Raissi - Scientific reports, 2022 - nature.com
Many technologies ranging from drug delivery approaches to tissue engineering purposes
are beginning to benefit from the unique ability of “smart polymers.” As a special case …

Investigation of nanotubes as the smart carriers for targeted delivery of mercaptopurine anticancer drug

M Zaboli, H Raissi, M Zaboli - Journal of Biomolecular Structure …, 2022 - Taylor & Francis
Mercaptopurine (MCP) is an anticancer drug that is used to treat acute lymphoblastic
leukemia. The therapeutic effect of the mercaptopurine limits its severe side effects like other …

Size-selective recognition by a tubular assembly of phenylene–pyrimidinylene alternated macrocycle through hydrogen-bonding interactions

D Xiao, D Zhang, B Chen, D Xie, Y Xiang, X Li, W Jin - Langmuir, 2015 - ACS Publications
Study of artificial tubular assemblies as a useful host scaffold for size-selective recognition
and release of guest molecules is an important subject in host–guest chemistry. We describe …

Mitochondrial delivery of doxorubicin by triphenylphosphonium-functionalized hyperbranched nanocarriers results in rapid and severe cytotoxicity

TA Theodossiou, Z Sideratou, ME Katsarou… - Pharmaceutical …, 2013 - Springer
Purpose To develop a novel hyperbranched polymer-based nanocarrier for efficient drug
delivery to cell mitochondria. Also to study for the first time the cytotoxic effect of doxorubicin …

Two-dimensionalcovalent triazine frameworks as superior nanocarriers for the delivery of thioguanine anti-cancer drugs: a periodic DFT study

R Rahimi, M Solimannejad… - New Journal of …, 2022 - pubs.rsc.org
This work aims to introduce a superior nanocarrier for thioguanine (TG) anti-cancer drug
delivery, drug release, and cancer therapy through computational chemistry. First, the …

Molecular dynamics study of a covalent organic framework as highly-efficient and biocompatible carriers for doxorubicin delivery: the role of nanopores

J Yu, X Jia, Y Yang, C Zhang, Y Liu… - Journal of Physics D …, 2021 - iopscience.iop.org
The development of highly-efficient loading, targeted delivery and controlled-release of drug
carrier systems is of great significance in tumor treatment. Although various kinds of nano …

Bilayer MSe2 and MS2 (M= Mo, W) as a novel drug delivery system for β-lapachone anticancer drug: Quantum chemical study

MH Mohammed, FH Hanoon - Computational and Theoretical Chemistry, 2020 - Elsevier
Transition metal dichalcogenides (TMDCs) considers a promising route in the biomedical
applications to deliver drugs. The mechanism of this study is utilized the Bilayer (BL) MSe 2 …