Nanotechnology-based approaches for targeting and delivery of drugs via Hexakis (m-PE) macrocycles
Abstract Hexakis (m-phenylene ethynylene)(m-PE) macrocycles, with aromatic backbones
and multiple hydrogen-bonding side chains, had a very high propensity to self-assemble via …
and multiple hydrogen-bonding side chains, had a very high propensity to self-assemble via …
New insights into Hexakis macrocycles as a novel nano-carrier for highly potent anti-cancer treatment: A new challenge in drug delivery
The purpose of this study is to design and evaluate a new tubular assembly structure of
Hexakis (m-phenylene ethynylene)(m-PE) macrocycles and to explore its potential …
Hexakis (m-phenylene ethynylene)(m-PE) macrocycles and to explore its potential …
Cation-pi interaction: A strategy for enhancing the performance of graphene-based drug delivery systems
To enhance the therapeutic properties of doxorubicin (DOX), a series of novel drug delivery
systems (DDS) based on the cation-π complex is designed. The effect of Li, Na, K, Be, and …
systems (DDS) based on the cation-π complex is designed. The effect of Li, Na, K, Be, and …
PNIPAM/Hexakis as a thermosensitive drug delivery system for biomedical and pharmaceutical applications
Many technologies ranging from drug delivery approaches to tissue engineering purposes
are beginning to benefit from the unique ability of “smart polymers.” As a special case …
are beginning to benefit from the unique ability of “smart polymers.” As a special case …
Investigation of nanotubes as the smart carriers for targeted delivery of mercaptopurine anticancer drug
Mercaptopurine (MCP) is an anticancer drug that is used to treat acute lymphoblastic
leukemia. The therapeutic effect of the mercaptopurine limits its severe side effects like other …
leukemia. The therapeutic effect of the mercaptopurine limits its severe side effects like other …
Size-selective recognition by a tubular assembly of phenylene–pyrimidinylene alternated macrocycle through hydrogen-bonding interactions
D Xiao, D Zhang, B Chen, D Xie, Y Xiang, X Li, W Jin - Langmuir, 2015 - ACS Publications
Study of artificial tubular assemblies as a useful host scaffold for size-selective recognition
and release of guest molecules is an important subject in host–guest chemistry. We describe …
and release of guest molecules is an important subject in host–guest chemistry. We describe …
Mitochondrial delivery of doxorubicin by triphenylphosphonium-functionalized hyperbranched nanocarriers results in rapid and severe cytotoxicity
TA Theodossiou, Z Sideratou, ME Katsarou… - Pharmaceutical …, 2013 - Springer
Purpose To develop a novel hyperbranched polymer-based nanocarrier for efficient drug
delivery to cell mitochondria. Also to study for the first time the cytotoxic effect of doxorubicin …
delivery to cell mitochondria. Also to study for the first time the cytotoxic effect of doxorubicin …
Two-dimensionalcovalent triazine frameworks as superior nanocarriers for the delivery of thioguanine anti-cancer drugs: a periodic DFT study
R Rahimi, M Solimannejad… - New Journal of …, 2022 - pubs.rsc.org
This work aims to introduce a superior nanocarrier for thioguanine (TG) anti-cancer drug
delivery, drug release, and cancer therapy through computational chemistry. First, the …
delivery, drug release, and cancer therapy through computational chemistry. First, the …
Molecular dynamics study of a covalent organic framework as highly-efficient and biocompatible carriers for doxorubicin delivery: the role of nanopores
J Yu, X Jia, Y Yang, C Zhang, Y Liu… - Journal of Physics D …, 2021 - iopscience.iop.org
The development of highly-efficient loading, targeted delivery and controlled-release of drug
carrier systems is of great significance in tumor treatment. Although various kinds of nano …
carrier systems is of great significance in tumor treatment. Although various kinds of nano …
Bilayer MSe2 and MS2 (M= Mo, W) as a novel drug delivery system for β-lapachone anticancer drug: Quantum chemical study
MH Mohammed, FH Hanoon - Computational and Theoretical Chemistry, 2020 - Elsevier
Transition metal dichalcogenides (TMDCs) considers a promising route in the biomedical
applications to deliver drugs. The mechanism of this study is utilized the Bilayer (BL) MSe 2 …
applications to deliver drugs. The mechanism of this study is utilized the Bilayer (BL) MSe 2 …