With the rapid development of nanotechnology as well as growing interest in
immunotherapy, a great number of vaccine delivery vehicles have been explored in order to …

Strategies of improving vaccine targeting ability toward lymph nodes have been attracting
considerable interest in recent years, though there are remaining delivery barriers based on …

Conspectus Development of vaccine technology that induces long lasting and potent
adaptive immune responses is of vital importance to combat emerging pathogens and to …

The need to optimize vaccine potency while minimizing toxicity in healthy recipients has
motivated studies of the formulation of vaccines to control how, when, and where antigens …

Vaccines have successfully eradicated a large number of diseases. However, some
infectious diseases (such as HIV, Chlamydia trachomatis or Bacillus anthracis) keep …

Nanoparticle delivery of subunit vaccines may increase vaccine efficacy, leading to a wide
variety of safe and effective vaccines beyond those available through dosing inactivated or …

Due to their ability to elicit a potent immune reaction with low systemic toxicity, cancer
vaccines represent a promising strategy for treating tumors. Considerable effort has been …

Cancer immunotherapies such as tumor vaccines, chimeric antigen receptor T cells and
immune checkpoint blockades, have attracted tremendous attention. Among them, tumor …

Vaccines provide a powerful tool to modulate the immune system for human disease
prevention and treatment. Classical vaccines mainly initiate immune responses in the lymph …

In cancer, lymph nodes (LNs) coordinate tumor antigen presentation necessary for effective
antitumor immunity, both at the levels of local cellular interactions and tissue-level …