Miltiradiene (1) is the precursor of phenolic diterpenoids such as ferruginol (2), requiring
aromatization and hydroxylation. While this has been attributed to a single cytochrome P450 …

Rosemary and sage species from Lamiaceae contain high amounts of structurally related
but diverse abietane diterpenes. A number of substances from this compound family have …

In plant terpene biosynthesis, oxidation of the hydrocarbon backbone produced by terpene
synthases is typically carried out by cytochrome P450 oxygenases (CYPs). The …

Limonoids are natural products made by plants belonging to the Meliaceae (Mahogany) and
Rutaceae (Citrus) families. They are well known for their insecticidal activity, contribution to …

Thymol and carvacrol are phenolic monoterpenes found in thyme, oregano, and several
other species of the Lamiaceae. Long valued for their smell and taste, these substances also …

Abstract Background Horehound (Marrubium vulgare) is a medicinal plant whose signature
bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential …

Plants use monoterpenols as precursors for the production of functionally and structurally
diverse molecules, which are key players in interactions with other organisms such as …

Cytochrome P450 monooxygenases (P450s) are important enzymes for generating some of
the enormous structural diversity of plant terpenoid secondary metabolites. In conifers …

Isoflavonoids are distributed predominantly in leguminous plants and play critical roles in
plant physiology. A cytochrome P450 (P450), 2-hydroxyisoflavanone synthase, is the key …

Terpene volatiles play important roles in plant-organism interactions as attractants of
pollinators or as defense compounds against herbivores. Among the most common plant …