[HTML][HTML] The ABA-LANCL1/2 Hormone-Receptors System Protects H9c2 Cardiomyocytes from Hypoxia-Induced Mitochondrial Injury via an AMPK-and NO-Mediated …

S Spinelli, L Guida, T Vigliarolo, M Passalacqua… - Cells, 2022 - mdpi.com
Abscisic acid (ABA) regulates plant responses to stress, partly via NO. In mammals, ABA
stimulates NO production by innate immune cells and keratinocytes, glucose uptake and …

[HTML][HTML] Abscisic Acid and Its Receptors LANCL1 and LANCL2 Control Cardiomyocyte Mitochondrial Function, Expression of Contractile, Cytoskeletal and Ion …

S Spinelli, L Guida, M Passalacqua, M Magnone… - Antioxidants, 2023 - mdpi.com
The cross-kingdom stress hormone abscisic acid (ABA) and its mammalian receptors
LANCL1 and LANCL2 regulate the response of cardiomyocytes to hypoxia by activating NO …

β2-adrenergic receptors mediate cardioprotection through crosstalk with mitochondrial cell death pathways

G Fajardo, M Zhao, G Berry, LJ Wong… - Journal of molecular and …, 2011 - Elsevier
β-adrenergic receptors (β-ARs) modulate cardiotoxicity/cardioprotection through crosstalk
with multiple signaling pathways. We have previously shown that β2-ARs are …

[HTML][HTML] LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells

L Sturla, C Fresia, L Guida, S Bruzzone, S Scarfì… - Journal of Biological …, 2009 - ASBMB
Abscisic acid (ABA) is a plant hormone regulating fundamental physiological functions in
plants, such as response to abiotic stress. Recently, ABA was shown to be produced and …

Adenine nucleotide translocase 1 overexpression protects cardiomyocytes against hypoxia via increased ERK1/2 and AKT activation

J Winter, I Klumpe, J Heger, U Rauch, HP Schultheiss… - Cellular signalling, 2016 - Elsevier
The influence of mitochondrial function on intracellular signalling is currently under intense
investigation. In this regard, we analysed the effect of adenine nucleotide translocase 1 …

Binding of abscisic acid to human LANCL2

L Sturla, C Fresia, L Guida, A Grozio, T Vigliarolo… - Biochemical and …, 2011 - Elsevier
The phytohormone abscisic acid (ABA) is the central regulator of abiotic stress in plants and
plays important roles during plant growth and development. In animal cells, ABA was shown …

Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo

L Sturla, E Mannino, S Scarfi, S Bruzzone… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Abscisic acid (ABA) is a plant hormone also present in animals, where it is involved in the
regulation of innate immune cell function and of glucose disposal, through its receptor …

[HTML][HTML] Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling

W Li, L Yin, X Sun, J Wu, Z Dong, K Hu, A Sun… - Cell death & …, 2020 - nature.com
Alpha-lipoic acid (α-LA), a well-known antioxidant, was proved to active ALDH2 in nitrate
tolerance and diabetic animal model. However, the therapeutic advantage of α-LA for heart …

[HTML][HTML] Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation

M Magnone, L Emionite, L Guida, T Vigliarolo… - Scientific reports, 2020 - nature.com
Abscisic acid (ABA) is a plant hormone active also in mammals where it regulates, at
nanomolar concentrations, blood glucose homeostasis. Here we investigated the …

[HTML][HTML] Lin28a protects against hypoxia/reoxygenation induced cardiomyocytes apoptosis by alleviating mitochondrial dysfunction under high glucose/high fat …

M Zhang, X Niu, J Hu, Y Yuan, S Sun, J Wang, W Yu… - PLoS …, 2014 - journals.plos.org
Aim The aim of the present study was to investigate the role of Lin28a in protecting against
hypoxia/reoxygenation (H/R)-induced cardiomyocytes apoptosis under high glucose/high fat …