XB130 is an adaptor protein that functions as a mediator of multiple tyrosine kinases
important for regulating cell proliferation, survival, migration and invasion. Formerly …

Several adaptor proteins have previously been shown to play an important role in the
promotion of tumourigenesis. XB130 (AFAP1L2) is an adaptor protein involved in many …

Adaptor proteins are functional proteins that contain two or more protein‑binding modules to
link signaling proteins together, which affect cell growth and shape and have no enzymatic …

XB130 is a novel oncoprotein that promotes cancer cell survival, proliferation and migration.
Its physiological function in vivo is largely unknown. The objective of this study was to …

XB130, a novel adaptor protein, mediates RET/PTC chromosome rearrangement-related
thyroid cancer cell proliferation and survival through phosphatidyl-inositol-3-kinase …

Adaptor proteins with multimodular structures can participate in the regulation of various
cellular functions. We have cloned a novel adaptor protein, XB130, which binds the p85α …

The expression of XB130 is associated with invasion and migration of many tumor cells, but
its roles in human colorectal cancer (CRC) remains unknown. To investigate this, protein …

XB130 is a cytosolic adaptor protein involved in various physiological processes and
oncogenesis of certain malignancies, but its role in the development of prostate cancer …

Identifying prognostic factors for osteosarcoma (OS) aids in the selection of patients who
require more aggressive management. XB130 is a newly characterized adaptor protein that …

Background XB130 has been reported to be expressed by various types of cells such as
thyroid cancer and esophageal cancer cells, and it promotes the proliferation and invasion …