Spinal protein kinase A and phosphorylated extracellular signal-regulated kinase signaling are involved in the antinociceptive effect of phytohormone abscisic acid in …

M Mollashahi, M Abbasnejad… - Arquivos de Neuro …, 2020 - SciELO Brasil
Objective: The phytohormone abscisic acid (ABA) as a signaling molecule exists in various
types of organisms from early multicellular to animal cells and tissues. It has been …

Phytohormone abscisic acid elicits antinociceptive effects in rats through the activation of opioid and peroxisome proliferator-activated receptors β/δ

M Mollashahi, M Abbasnejad… - European journal of …, 2018 - Elsevier
The phytohormone abscisic acid exists in animal tissues particularly in the brain. However,
its neurophysiological effects have not yet been fully clarified. This study was designed to …

Phosphatidylinositol-3-kinase and protein kinase C are involved in the pro-cognitive and anti-anxiety effects of phytohormone abscisic acid in rats

R Naderi, S Esmaeili-Mahani, M Abbasnejad - Biomedicine & …, 2017 - Elsevier
The phytohormone abscisic acid (ABA) exists in animal tissues particularly in the brain.
However, the neurophysiological effects of ABA have not yet been fully determined …

Electroacupuncture inhibits phosphorylation of spinal phosphatidylinositol 3-kinase/Akt in a carrageenan-induced inflammatory rat model

HN Kim, YR Kim, JY Jang, HK Shin, BT Choi - Brain Research Bulletin, 2012 - Elsevier
We investigated the changes of pain-related spinal signaling pathway after
electroacupuncture (EA) stimulation in a carrageenan-induced rat model. EA stimulation …

Electroacupuncture mediates extracellular signal-regulated kinase 1/2 pathways in the spinal cord of rats with inflammatory pain

JQ Fang, JF Fang, Y Liang, JY Du - BMC Complementary and Alternative …, 2014 - Springer
Background Activation of extracellular signal-regulated kinase1/2 (ERK1/2) in dorsal horn of
the spinal cord by peripheral inflammation is contributed to inflammatory pain …

Inhibition of ERK phosphorylation by substance P N-terminal fragment decreases capsaicin-induced nociceptive response

T Komatsu, H Mizoguchi, M Sasaki, C Sakurada… - …, 2011 - Elsevier
Previous research has demonstrated that substance P N-terminal fragments produced by
the action of several different enzymes in the spinal cord could reduce nociception when …

Antinociceptive effect of N-(9, 13b-dihydro-1H-dibenzo [c, f] imidazo [1, 5-a] azepin-3-yl)-2-hydroxybenzamide on different pain models in mice

HJ Lee, HM Lim, JH Feng, JM Lee, JT Lee… - Brazilian Journal of …, 2022 - SciELO Brasil
Abstract N-(9, 13b-dihydro-1H-dibenzo [c, f] imidazo [1, 5-a] azepin-3-yl)-2-
hydroxybenzamide (DDIAHB) is a new drug developed through molecular modelling and …

[HTML][HTML] Extracellular calcium influx through L-type calcium channels, intracellular calcium currents and extracellular signal-regulated kinase signaling are involved in …

R Naderi, S Esmaeili-Mahani, M Abbasnejad - Biomedicine & …, 2019 - Elsevier
Abscisic acid (ABA), a critical phytohormone, is also produced in animal tissues. It has been
reported that ABA has pro-cognitive and anti-anxiety effects in rats. However, its detailed …

Oral treatment with methanolic extract of the root bark of Condalia buxifolia Reissek alleviates acute pain and inflammation in mice: Potential interactions with PGE2 …

RR Simões, I dos Santos Coelho… - Journal of …, 2016 - Elsevier
Abstract Ethnopharmacological relevance The Condalia buxifolia root bark infusion is used
in traditional medicine in Brazil as antipyretic, anti-inflammatory and anti-dysentery. Previous …

[HTML][HTML] From peripheral to central: the role of ERK signaling pathway in acupuncture analgesia

JY Park, JJ Park, S Jeon, AR Doo, SN Kim, H Lee… - The Journal of …, 2014 - Elsevier
Despite accumulating evidence of the clinical effectiveness of acupuncture, its mechanism
remains largely unclear. We assume that molecular signaling around the acupuncture …