Bisphenol A causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio)

LV Laing, J Viana, EL Dempster, M Trznadel… - Epigenetics, 2016 - Taylor & Francis
Bisphenol A (BPA) is a commercially important high production chemical widely used in
epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous …

Global DNA methylation in gonads of adult zebrafish Danio rerio under bisphenol A exposure

Y Liu, Y Zhang, S Tao, Y Guan, T Zhang… - … and environmental safety, 2016 - Elsevier
Altered DNA methylation is pervasively associated with changes in gene expression and
signal transduction after exposure to a wide range of endocrine disrupting chemicals. As a …

[HTML][HTML] Associations between behavioral effects of bisphenol A and DNA methylation in zebrafish embryos

PA Olsvik, P Whatmore, SJ Penglase… - Frontiers in …, 2019 - frontiersin.org
Endocrine-disrupting contaminants have been associated with aberrant changes in
epigenetic pathways in animals. In this study, zebrafish embryos were exposed bisphenol A …

Reproductive toxicity of low level bisphenol A exposures in a two-generation zebrafish assay: evidence of male-specific effects

J Chen, Y Xiao, Z Gai, R Li, Z Zhu, C Bai, RL Tanguay… - Aquatic Toxicology, 2015 - Elsevier
Bisphenol A (BPA), a high-volume chemical used to make polycarbonate plastic and epoxy
resins, is a ubiquitous contaminant in environment and human body. To investigate the …

Genetic evidence for estrogenicity of bisphenol A in zebrafish gonadal differentiation and its signalling mechanism

W Song, H Lu, K Wu, Z Zhang, ESW Lau… - Journal of hazardous …, 2020 - Elsevier
Bisphenol A (BPA) can induce endocrine disorders in humans and animals. In this study, we
used several zebrafish mutants deficient in estrogen production and signalling, which could …

Male exposure to bisphenol a impairs spermatogenesis and triggers histone hyperacetylation in zebrafish testes

S González-Rojo, M Lombó, C Fernández-Díez… - Environmental …, 2019 - Elsevier
Bisphenol A (BPA) is an endocrine disruptor whose ubiquitous presence in the environment
has been related with impairment of male reproduction. BPA can cause both transcriptomic …

Transgenerational effects of BPA on female reproduction

S Santangeli, C Consales, F Pacchierotti… - Science of the total …, 2019 - Elsevier
Bisphenol A (BPA) is an abundant environmental contaminant and studies have shown the
presence of BPA in the urine of over 90% of population tested in Canada and USA. In …

[HTML][HTML] BPA-induced deregulation of epigenetic patterns: effects on female zebrafish reproduction

S Santangeli, F Maradonna, G Gioacchini… - Scientific Reports, 2016 - nature.com
Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It
interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic …

[HTML][HTML] Genetic and epigenetic alterations induced by bisphenol A exposure during different periods of spermatogenesis: from spermatozoa to the progeny

M Lombó, C Fernández-Díez, S González-Rojo… - Scientific Reports, 2019 - nature.com
Exposure to bisphenol A (BPA) has been related to male reproductive disorders. Since this
endocrine disruptor also displays genotoxic and epigenotoxic effects, it likely alters the …

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
Abstract Benzo [a] pyrene (BaP) is an established carcinogen and reproductive and
developmental toxicant. BaP exposure in humans and animals has been linked to infertility …