[HTML][HTML] A review of respiratory anatomical development, air flow characterization and particle deposition

MS Islam, G Paul, HX Ong, PM Young, YT Gu… - International journal of …, 2020 - mdpi.com
The understanding of complex inhalation and transport processes of pollutant particles
through the human respiratory system is important for investigations into dosimetry and …

Pulmonary aerosol transport and deposition analysis in upper 17 generations of the human respiratory tract

MS Islam, SC Saha, E Sauret, T Gemci, YT Gu - Journal of Aerosol Science, 2017 - Elsevier
The major problem in understanding the therapeutically targeted drug delivery system in the
deeper airways of the human lung is the lack of adequate data of particle transport and …

An in silico inter-subject variability study of extra-thoracic morphology effects on inhaled particle transport and deposition

Y Feng, J Zhao, C Kleinstreuer, Q Wang, J Wang… - Journal of Aerosol …, 2018 - Elsevier
An understanding of human inter-subject variability is crucial for the implementation of
personalized pulmonary drug delivery as well as exposure assessment of airborne …

Computational modeling of aerosol deposition in respiratory tract: a review

AA Rostami - Inhalation toxicology, 2009 - Taylor & Francis
This review article is intended to serve as an overview of the current status of the
computational tools and approaches available for predicting respiratory-tract dosimetry of …

Computationally efficient analysis of particle transport and deposition in a human whole-lung-airway model. Part I: Theory and model validation

AV Kolanjiyil, C Kleinstreuer - Computers in biology and medicine, 2016 - Elsevier
Computational predictions of aerosol transport and deposition in the human respiratory tract
can assist in evaluating detrimental or therapeutic health effects when inhaling toxic …

Characterization of regional and local deposition of inhaled aerosol drugs in the respiratory system by computational fluid and particle dynamics methods

Á Farkas, I Balásházy, K Szőcs - Journal of aerosol medicine, 2006 - liebertpub.com
The present work describes the local deposition patterns of therapeutic aerosols in the
oropharyngeal airways, healthy and diseased bronchi and alveoli using computational fluid …

In Vivo–In Vitro Correlations: Predicting Pulmonary Drug Deposition from Pharmaceutical Aerosols

PR Byron, M Hindle, CF Lange… - Journal of aerosol …, 2010 - liebertpub.com
In order to answer the question “what research remains to be done?” we review the current
state of the art in pharmaceutical aerosol deposition modeling and explore possible in vivo …

Recent advances in predictive understanding of respiratory tract deposition

WH Finlay, AR Martin - Journal of Aerosol Medicine and Pulmonary …, 2008 - liebertpub.com
Accurate prediction of respiratory tract deposition is important in gauging the health risks of
ambient bioaerosols and environmental aerosols, as well as in developing pharmaceutical …

Comparative numerical modeling of inhaled micron-sized particle deposition in human and rat nasal cavities

Y Shang, J Dong, K Inthavong, J Tu - Inhalation Toxicology, 2015 - Taylor & Francis
Micron-sized particle deposition in anatomically realistic models of a rat and human nasal
cavity was numerically investigated. A steady laminar inhalation flow rate was applied and …

Modeling airflow and particle transport/deposition in pulmonary airways

C Kleinstreuer, Z Zhang, Z Li - Respiratory physiology & neurobiology, 2008 - Elsevier
A review of research papers is presented, pertinent to computer modeling of airflow as well
as nano-and micron-size particle deposition in pulmonary airway replicas. The key modeling …