Objective: The TGFB1 gene is among the most studied genes in high myopia due to its role
in scleral remodeling. But reported findings of association on TGFB1 and high myopia are …

Objective To investigate the genetic association between transforming growth factor β1
(TGFB1) gene polymorphisms and high myopia in a Chinese population. Methods Six …

Excessive axial elongation in progressive high myopia is associated with scleral remodeling
events resulting in diminished sclera-fibril architecture of the eye. Transforming Growth …

Method: Four hundred twelve articles were identified, of which 11 articles with 5213
participants in 4 countries were included in the final analysis. Review Manager software …

Purpose: Transforming growth factor-β (TGFβ), a multifunctional growth factor that plays a
key role in the remodeling of scleral tissue, may be involved in the predisposition and …

Methods. The Singapore Cohort Study for Risk Factors in Myopia cohort has been
previously described. 3, 4 The students enrolled in the study are examined annually, and …

This study aims to investigate the associations of SNPs in the mammalian target of
rapamycin (MTOR) and the platelet derived growth factor receptor alpha (PDGFRA) genes …

purpose. Transforming growth β-induced factor (TGIF) has been identified as a candidate
gene for high myopia through genetic linkage studies and through its role in ocular growth in …

Purpose: High myopia is a complex disorder that imposes serious consequences on ocular
health. Linkage analysis has identified several genetic loci with a series of potential …

purpose. To investigate the coding exons of transforming growth factor (TGF)-β–induced
factor (TGIF) for mutations in Chinese patients with high myopia. methods. Seventy-one …