[HTML][HTML] Strain-level epidemiology of microbial communities and the human microbiome

Y Yan, LH Nguyen, EA Franzosa, C Huttenhower - Genome medicine, 2020 - Springer
The biological importance and varied metabolic capabilities of specific microbial strains
have long been established in the scientific community. Strains have, in the past, been …

Microbiome epidemiology and association studies in human health

H VanEvery, EA Franzosa, LH Nguyen… - Nature Reviews …, 2023 - nature.com
Studies of the human microbiome share both technical and conceptual similarities with
genome-wide association studies and genetic epidemiology. However, the microbiome has …

[HTML][HTML] Experimental design and quantitative analysis of microbial community multiomics

H Mallick, S Ma, EA Franzosa, T Vatanen, XC Morgan… - Genome biology, 2017 - Springer
Studies of the microbiome have become increasingly sophisticated, and multiple sequence-
based, molecular methods as well as culture-based methods exist for population-scale …

[HTML][HTML] A framework for human microbiome research

nature, 2012 - nature.com
A variety of microbial communities and their genes (the microbiome) exist throughout the
human body, with fundamental roles in human health and disease. The National Institutes of …

[HTML][HTML] The healthy human microbiome

J Lloyd-Price, G Abu-Ali, C Huttenhower - Genome medicine, 2016 - Springer
Humans are virtually identical in their genetic makeup, yet the small differences in our DNA
give rise to tremendous phenotypic diversity across the human population. By contrast, the …

The human microbiome: our second genome

EA Grice, JA Segre - Annual review of genomics and human …, 2012 - annualreviews.org
The human genome has been referred to as the blueprint of human biology. In this review
we consider an essential but largely ignored overlay to that blueprint, the human …

[HTML][HTML] The microbiome in precision medicine: the way forward

JF Petrosino - Genome medicine, 2018 - Springer
Editorial summary Novel associations between the human microbiome and health and
disease are routinely emerging, and important host–microbiome interactions are targets for …

[HTML][HTML] Moving pictures of the human microbiome

JG Caporaso, CL Lauber, EK Costello, D Berg-Lyons… - Genome biology, 2011 - Springer
Background Understanding the normal temporal variation in the human microbiome is
critical to developing treatments for putative microbiome-related afflictions such as obesity …

[PDF][PDF] A framework for human microbiome research

BLC SA - Nature, 2012 - core.ac.uk
A variety of microbial communities and their genes (microbiome) exist throughout the human
body, playing fundamental roles in human health and disease. The NIH funded Human …

Sequencing the human microbiome in health and disease

MJ Cox, WOCM Cookson… - Human molecular …, 2013 - academic.oup.com
Molecular techniques have revolutionized the practice of standard microbiology. In
particular, 16S rRNA sequencing, whole microbial genome sequencing and metagenomics …