Novel vaccination strategies against tuberculosis

P Andersen, SHE Kaufmann - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
The tuberculosis (TB) pandemic continues to rampage despite widespread use of the BCG
(Bacillus Calmette–Guérin) vaccine. Novel vaccination strategies are urgently needed to …

Moving tuberculosis vaccines from theory to practice

P Andersen, TJ Scriba - Nature Reviews Immunology, 2019 - nature.com
Tuberculosis (TB) vaccine research has reached a unique point in time. Breakthrough
findings in both the basic immunology of Mycobacterium tuberculosis infection and the …

TB vaccines: progress and problems

P Andersen - Trends in immunology, 2001 - cell.com
Tuberculosis (TB) is the biggest killer worldwide of any infectious disease, a situation
worsened by the advent of the HIV epidemic and the emergence of multi-drug resistant …

Tuberculosis vaccines in clinical trials

R Rowland, H McShane - Expert review of vaccines, 2011 - Taylor & Francis
Effective prophylactic and/or therapeutic vaccination is a key strategy for controlling the
global TB epidemic. The partial effectiveness of the existing TB vaccine, bacille Calmette …

Tuberculosis: vaccines in the pipeline

LH Ly, DN McMurray - Expert Review of Vaccines, 2008 - Taylor & Francis
TB is presenting new challenges as a global health problem, especially with new threats of
HIV coinfection and multidrug-resistant and extensively drug-resistant strains of …

[HTML][HTML] Vaccination against tuberculosis: revamping BCG by molecular genetics guided by immunology

SHE Kaufmann - Frontiers in immunology, 2020 - frontiersin.org
Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for
almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines …

The current status, challenges, and future developments of new tuberculosis vaccines

W Gong, Y Liang, X Wu - Human vaccines & immunotherapeutics, 2018 - Taylor & Francis
Mycobacterium tuberculosis complex causes tuberculosis (TB), one of the top 10 causes of
death worldwide. TB results in more fatalities than multi-drug resistant (MDR) HIV strain …

Novel tuberculosis vaccines on the horizon

SK Parida, SHE Kaufmann - Current opinion in immunology, 2010 - Elsevier
Eleven new tuberculosis (TB) vaccines are in various phases of clinical trials. These include
subunit vaccines to improve the current vaccine BCG, and recombinant BCG to substitute for …

Tuberculosis vaccine development: progress in clinical evaluation

SB Sable, JE Posey, TJ Scriba - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Tuberculosis (TB) is the leading killer among all infectious diseases worldwide despite
extensive use of the Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine. A safer …

An overview of the development of new vaccines for tuberculosis

E Whitlow, AS Mustafa, SNM Hanif - Vaccines, 2020 - mdpi.com
Currently, there is only one licensed vaccine against tuberculosis (TB), the Bacillus Calmette–
Guérin (BCG). Despite its protective efficacy against TB in children, BCG has failed to protect …