Abstract Cyclooxygenase-2 (COX-2) and its metabolite prostaglandin E2 (PGE2) can
potentially affect most of the events in cancer development, including promotion of …

AIM: To investigate the anti-tumor effects of paeonol in gastric cancer cell proliferation and
apoptosis in vitro and in vivo. METHODS: Murine gastric cancer cell line mouse forestomach …

AIM: To investigate the effect of paeonol on controlling the proliferation of colorectal cancer
cell line HT-29 and to discuss its possible mechanism. METHODS: The inhibitory effect of …

Paeonol is a simple phenolic compound isolated from herbal root bark, which has been
reported to possess numerous biological and pharmacological characteristics, including a …

Paeonol, a major phenolic component of Moutan Cortex, is known to have antitumor effects
through an unknown mechanism. In this study, we tried to elucidate the anticancer effects of …

Background: Targeting inflammatory microenvironment is a promising anti-tumor strategy.
Paeonol is a phenolic compound with effective anti-inflammatory and anti-tumor properties …

AIM: To investigate the antiproliferative effect of paeonol (Pae) used alone or in combination
with chemotherapeutic agents [cisplatin (CDDP), doxorubicin (DOX) and 5-fluorouracil (5 …

Paeonol is a major phenolic micromolecular component of Moutan cortex Radicis, a
traditional Chinese Medicine. It has shown antitumor effects in previous studies; however …

The purpose of the present study was to analyze the association between paeonol and the
known genes related to gastric cancer (GC) using bioinformatics methods, and to investigate …

The incidence of esophageal cancer (EC), especially adenocarcinoma, has increased
tremendously in Western countries and the prognosis of EC remains poor. Paeonol (Pae), a …