Differential coding of reward and movement information in the dorsomedial striatal direct and indirect pathways
The direct and indirect pathways of the basal ganglia have long been thought to mediate
behavioral promotion and inhibition, respectively. However, this classic dichotomous model …
behavioral promotion and inhibition, respectively. However, this classic dichotomous model …
Gain modulation by corticostriatal and thalamostriatal input signals during reward-conditioned behavior
The cortex and thalamus send excitatory projections to the striatum, but little is known about
how these inputs, either individually or collectively, regulate striatal dynamics during …
how these inputs, either individually or collectively, regulate striatal dynamics during …
Monitoring and updating of action selection for goal-directed behavior through the striatal direct and indirect pathways
S Nonomura, K Nishizawa, Y Sakai, Y Kawaguchi… - Neuron, 2018 - cell.com
The basal ganglia play key roles in adaptive behaviors guided by reward and punishment.
However, despite accumulating knowledge, few studies have tested how heterogeneous …
However, despite accumulating knowledge, few studies have tested how heterogeneous …
Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways
A Rios, S Nonomura, S Kato, J Yoshida… - Communications …, 2023 - nature.com
Neurons comprising nigrostriatal system play important roles in action selection. However, it
remains unclear how this system integrates recent outcome information with current action …
remains unclear how this system integrates recent outcome information with current action …
Temporally restricted dopaminergic control of reward-conditioned movements
K Lee, LD Claar, A Hachisuka, KI Bakhurin… - Nature …, 2020 - nature.com
Midbrain dopamine (DA) neurons encode both reward-and movement-related events and
are implicated in disorders of reward processing as well as movement. Consequently …
are implicated in disorders of reward processing as well as movement. Consequently …
Opponent control of behavior by dorsomedial striatal pathways depends on task demands and internal state
A classic view of the striatum holds that activity in direct and indirect pathways oppositely
modulates motor output. Whether this involves direct control of movement, or reflects a …
modulates motor output. Whether this involves direct control of movement, or reflects a …
Dorsal striatal–midbrain connectivity in humans predicts how reinforcements are used to guide decisions
It has been suggested that the target areas of dopaminergic midbrain neurons, the dorsal
(DS) and ventral striatum (VS), are differently involved in reinforcement learning especially …
(DS) and ventral striatum (VS), are differently involved in reinforcement learning especially …
Direct and indirect dorsolateral striatum pathways reinforce different action strategies
The basal ganglia, and the striatum in particular, are critical for action reinforcement [1, 2].
The dorsal striatum, which can be further subdivided into dorsomedial (DMS) and …
The dorsal striatum, which can be further subdivided into dorsomedial (DMS) and …
Reward prediction error signaling in posterior dorsomedial striatum is action specific
TA Stalnaker, GG Calhoon, M Ogawa… - Journal of …, 2012 - Soc Neuroscience
Neural correlates of reward prediction errors (RPEs) have been found in dorsal striatum.
Such signals may be important for updating associative action representations within …
Such signals may be important for updating associative action representations within …
Response inhibition signals and miscoding of direction in dorsomedial striatum
The ability to inhibit action is critical for everyday behavior and is affected by a variety of
disorders. Behavioral control and response inhibition is thought to depend on a neural …
disorders. Behavioral control and response inhibition is thought to depend on a neural …