The cortical angioarchitecture is a key factor in controlling cerebral blood flow and oxygen
metabolism. Difficulties in imaging the complex microanatomy of the cortex have so far …

The precise modulation of regional cerebral blood flow during neural activation is important
for matching local energetic demand and supply and clearing brain metabolites. Here we …

A better knowledge of the flow and pressure distribution in realistic microvascular networks
is needed for improving our understanding of neurovascular coupling mechanisms and the …

Capillary perfusion in the brain is characterized by an essentially continuous flow of
erythrocytes and plasma in almost all capillaries. Rapid fluctuations and spatial …

The spatiotemporal evolution of cerebral microcirculatory adjustments to functional brain
stimulation is the fundamental determinant of the functional specificity of hemodynamically …

We review the organizational principles of the cortical vasculature and the underlying
patterns of blood flow under normal conditions and in response to occlusion of single …

Our understanding of how capillary blood flow and oxygen distribute across cortical layers to
meet the local metabolic demand is incomplete. We addressed this question by using two …

The three-dimensional spatial arrangement of the cortical microcirculatory system is critical
for understanding oxygen exchange between blood vessels and brain cells. A three …

How neuronal activity changes cerebral blood flow is of biological and practical importance.
The rodent whisker-barrel system has special merits as a model for studies of changes in …

Cortical blood flow at the level of individual capillaries and the coupling of neuronal activity
to flow in capillaries are fundamental aspects of homeostasis in the normal and the diseased …