Cardioprotective effects of early and late aerobic exercise training in experimental pulmonary arterial hypertension

D Moreira-Gonçalves, R Ferreira, H Fonseca… - Basic research in …, 2015 - Springer
Clinical studies suggest that aerobic exercise can exert beneficial effects in pulmonary
arterial hypertension (PAH), but the underlying mechanisms are largely unknown. We …

Exercise training and pulmonary arterial hypertension: A review of the cardiac benefits

LL Soares, FR Drummond, VN Lavorato… - Science & Sports, 2018 - Elsevier
Aims Patients of pulmonary arterial hypertension (PAH) exhibit reduced functional capacity
and exercise tolerance. Despite the evidences that exercise training is beneficial to this …

Continuous aerobic exercise prevents detrimental remodeling and right heart myocyte contraction and calcium cycling dysfunction in pulmonary artery hypertension

F de Jesus Silva, FR Drummond… - Journal of …, 2021 - journals.lww.com
Pulmonary artery hypertension (PAH) imposes right heart and lung detrimental remodeling
which impairs cardiac contractility, physical effort tolerance, and survival. The effects of an …

Opposite effects of training in rats with stable and progressive pulmonary hypertension

ML Handoko, FS De Man, CM Happe, I Schalij… - Circulation, 2009 - Am Heart Assoc
Background—Exercise training in pulmonary arterial hypertension (PH) is a promising
adjunct to medical treatment. However, it is still unclear whether training is beneficial for all …

Effects of exercise training on pulmonary hemodynamics, functional capacity and inflammation in pulmonary hypertension

MJ Richter, J Grimminger, B Krüger… - Pulmonary …, 2017 - journals.sagepub.com
Pulmonary hypertension (PH) is characterized by severe exercise limitation mainly attributed
to the impairment of right ventricular function resulting from a concomitant elevation of …

High-intensity interval training, but not continuous training, reverses right ventricular hypertrophy and dysfunction in a rat model of pulmonary hypertension

MB Brown, E Neves, G Long, J Graber… - American Journal …, 2017 - journals.physiology.org
Exercise is beneficial in pulmonary arterial hypertension (PAH), although studies to date
indicate little effect on the elevated pulmonary pressures or maladaptive right ventricle (RV) …

Resistance exercise training benefits pulmonary, cardiac, and muscular structure and function in rats with stable pulmonary artery hypertension

LL Soares, LB Leite, LOG Ervilha, BRA Pelozin… - Life Sciences, 2023 - Elsevier
Aim We tested the effects of low-to moderate-intensity resistance exercise training (RT) on
the structure and function of pulmonary, right ventricle (RV), and skeletal muscle tissues in …

Novel assessment of haemodynamic kinetics with acute exercise in a rat model of pulmonary arterial hypertension

MB Brown, TJ Chingombe, AB Zinn… - Experimental …, 2015 - Wiley Online Library
New Findings What is the central question of this study? The acute effect of exercise at
moderately high intensity on already‐elevated pulmonary arterial pressures and right …

Effects of different types of exercise training on pulmonary arterial hypertension: a systematic review

L Waller, K Krüger, K Conrad, A Weiss… - Journal of Clinical …, 2020 - mdpi.com
Pulmonary arterial hypertension (PAH) represents a chronic progressive disease
characterized by high blood pressure in the pulmonary arteries leading to right heart failure …

Exercise training contributes to H2O2/VEGF signaling in the lung of rats with monocrotaline-induced pulmonary hypertension

R Colombo, R Siqueira, A Conzatti… - Vascular …, 2016 - Elsevier
Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling
and right ventricle overload. Given that angiogenesis is a key factor involved in the reduction …