IL-23/IL-17 Axis in Chronic Hepatitis C and non-alcoholic steatohepatitis—new insight into immunohepatotoxicity of different Chronic Liver diseases

A Vujovic, AM Isakovic, S Misirlic-Dencic… - International Journal of …, 2023 - mdpi.com
Considering the relevance of the research of pathogenesis of different liver diseases, we
investigated the possible activity of the IL-23/IL-17 axis on the immunohepatotoxicity of two …

Serum cytokine of IL‐10 and IL‐12 in chronic liver disease: the immune and inflammatory response

HM El-Emshaty, WA Nasif, IE Mohamed - Disease Markers, 2015 - Wiley Online Library
The current study was designed to investigate the potential association of serum interleukin‐
10 and interleukin‐12 with HCV infection in chronic liver disease and to evaluate their …

Association between plasma interleukin-18 levels and liver injury in chronic hepatitis C virus infection and non-alcoholic fatty liver disease

J Vecchiet, K Falasca, P Cacciatore… - Annals of Clinical & …, 2005 - Assoc Clin Scientists
There is significant upregulation of interleukin-18 (IL-18) expression in viral infectious
diseases and in some chronic hepatic diseases, especially (i) hepatitis C virus (HCV) …

Correlation Analysis of IL-17, IL-21, IL-23 with Non-Alcoholic Liver Fibrosis and Cirrhosis

X Yang, L Liao, Z Liang, S Yu, Z Guo - Journal of Inflammation …, 2024 - Taylor & Francis
Objective This research aimed to explore the involvement of interleukins (IL)-IL-6, IL-17, IL-
21, and IL-23-in the evolution and diagnosis of non-alcoholic liver fibrosis and cirrhosis …

Serum levels of IL‐33 and correlation with IL‐4, IL‐17A, and hypergammaglobulinemia in patients with autoimmune hepatitis

M Liang, Z Liwen, Z Yun, D Yanbo… - Mediators of …, 2018 - Wiley Online Library
This study investigated the role of IL‐33 in the pathogenesis of autoimmune hepatitis (AIH).
The levels of IL‐33/sST2 and Th1/Th2/Th17‐type cytokines were determined by enzyme …

Interleukin-21 plays a critical role in the pathogenesis and severity of type I autoimmune hepatitis

K Abe, A Takahashi, H Imaizumi, M Hayashi, K Okai… - Springerplus, 2016 - Springer
Background and aims Recently, the number of follicular helper T (Tfh) cells expressing
interleukin (IL)-21 was found to increase in peripheral blood of human and murine models of …

The roles of serum IL-18, IL-10, TNF-alpha and sIL-2R in patients with chronic hepatitis C.

HY Jia, J Du, SH Zhu, YJ Ma, HY Chen… - Hepatobiliary & …, 2002 - europepmc.org
OBJECTIVE: To identify the roles of serum IL-18, IL-10, TNF-alpha and sIL-2R in the
pathogenesis of chronic hepatitis C and the effects of interferon on the mentioned serum …

IL-17A in human liver: significant source of inflammation and trigger of liver fibrosis initiation

D Kartasheva-Ebertz, J Gaston, L Lair-Mehiri… - International Journal of …, 2022 - mdpi.com
IL-17A is considered to guide liver inflammation and fibrosis. From twenty-two human liver
samples of different fibrosis stages (F0 to F4), IL-17A, IL-22, and TGFβ1 protein expression …

[HTML][HTML] Association between serum IL-6, IL-10, IL-12, and IL-23 levels and severity of liver cirrhosis

I Rey - Medical Archives, 2021 - ncbi.nlm.nih.gov
Background: Liver cirrhosis contributes to high liver-related mortality globally. Systemic
inflammation mediated by immune cells contributes to the progression of liver cirrhosis …

Involvement of the interleukin-23/interleukin-17 axis in chronic hepatitis C virus infection and its treatment responses

P Meng, S Zhao, X Niu, N Fu, S Su, R Wang… - International Journal of …, 2016 - mdpi.com
Interleukin-23 (IL-23) and its downstream factor IL-17 are the key cytokines involved in
immune and inflammatory response in chronic liver diseases. This study aimed to …