Detection of abnormal behaviors in prenatal Poly (I: C) exposed mice in a group‐rearing environment

M Komada, N Kiriyama, R Sugiyama… - Congenital …, 2024 - Wiley Online Library
During pregnancy, the maternal environment is critical for normal ontogeny and central
nervous system development. Occasionally, prenatal exposure to environmental factors …

Age‐related changes in behavior profile in male offspring of rats treated with poly I: C‐induced maternal immune activation in early gestation

T Chen, H Meng, N Fang, P Shi, M Chen… - Animal Models and …, 2024 - Wiley Online Library
Background Autism and schizophrenia are environmental risk factors associated with
prenatal viral infection during pregnancy. It is still unclear whether behavior phenotypes …

[HTML][HTML] Induction of maternal immune activation in mice at mid-gestation stage with viral mimic poly (I: C)

KH Chow, Z Yan, WL Wu - Journal of visualized experiments: JoVE, 2016 - ncbi.nlm.nih.gov
Maternal immune activation (MIA) model is increasingly well appreciated as a rodent model
for the environmental risk factor of various psychiatric disorders. Numerous studies have …

Sex-dependent behavioral alterations in a poly (I: C)-induced maternal immune activation mouse model without segment filamentous bacteria

S Fujii, Y Murata, Y Imamura, Y Nakachi, M Bundo… - Neuroscience …, 2023 - Elsevier
Maternal immune activation is one of the environmental risk factors for offspring to develop
psychiatric disorders. A synthetic viral mimetic immunogen, polyinosinic-polycytidylic acid …

The different effects of LPS and poly I: C prenatal immune challenges on the behavior, development and inflammatory responses in pregnant mice and their offspring

D Arsenault, I St-Amour, G Cisbani… - Brain, behavior, and …, 2014 - Elsevier
In recent years, in vivo animal models of prenatal infection have been developed in an
attempt to recreate behavioral and neuropathological features associated to a number of …

[HTML][HTML] Gender-dependent effects of maternal immune activation on the behavior of mouse offspring

ICY Xuan, DR Hampson - PloS one, 2014 - journals.plos.org
Autism spectrum disorders are neurodevelopmental disorders characterized by two core
symptoms; impaired social interactions and communication, and ritualistic or repetitive …

[HTML][HTML] The effect of maternal immune activation on social play-induced ultrasonic vocalization in rats

K Gzielo, A Potasiewicz, E Litwa, D Piotrowska, P Popik… - Brain sciences, 2021 - mdpi.com
Prenatal maternal infection is associated with an increased risk of various
neurodevelopmental disorders, including autism spectrum disorders (ASD). Maternal …

Prenatal exposure to the viral mimetic poly I: C alters fetal brain cytokine expression and postnatal behaviour

U Ratnayake, T Quinn, DA LaRosa… - Developmental …, 2014 - karger.com
An increased incidence of mental illness disorders is found in children and adolescents born
to mothers who experienced an infection-based illness during pregnancy. Animal models to …

[HTML][HTML] Maternal immune activation affects socio-communicative behavior in adult rats

K Gzieło, D Piotrowska, E Litwa, P Popik, A Nikiforuk - Scientific reports, 2023 - nature.com
A wide body of evidence suggests a relationship between maternal immune activation (MIA)
and neurodevelopmental disorders such as autism spectrum disorder (ASD). Since social …

Sex-dependent behavioral alterations in a poly (I: C)-induced maternal immune activation model without segment filamentous bacteria

K Iwamoto, M Bundo, Y Murata, Y Imamura, Y Nakachi… - 2023 - researchsquare.com
Maternal immune activation is one of the major environmental risk factors for offspring to
develop psychiatric disorders. A synthetic viral mimetic immunogen, polyinosinic …