[HTML][HTML] Analysis of circulating extracellular vesicle derived microRNAs in breast cancer patients with obesity: a potential role for Let-7a

I Barone, L Gelsomino, FM Accattatis… - Journal of Translational …, 2023 - Springer
Background The incidence of obesity, a known risk factor for several metabolic and chronic
diseases, including numerous malignancies, has risen sharply in the world. Various clinical …

[HTML][HTML] miRNAs in the Box: Potential Diagnostic Role for Extracellular Vesicle-Packaged miRNA-27a and miRNA-128 in Breast Cancer

C Giordano, FM Accattatis, L Gelsomino… - International Journal of …, 2023 - mdpi.com
Circulating extracellular vesicle (EV)-derived microRNAs (miRNAs) are now considered the
next generation of cancer “theranostic” tools, with strong clinical relevance. Although their …

[HTML][HTML] Obesity impacts the regulation of miR-10b and its targets in primary breast tumors

A Meerson, Y Eliraz, H Yehuda, B Knight, M Crundwell… - BMC cancer, 2019 - Springer
Background Obesity increases breast cancer (BC) risk in post-menopausal women by
mostly unknown molecular mechanisms which may partly be regulated by microRNAs …

[HTML][HTML] Obesity, leptin, and deregulation of microRNA in lipid metabolisms: their contribution to breast cancer prognosis

KW Taroeno-Hariadi, MS Hardianti, H Sinorita… - Diabetology & Metabolic …, 2021 - Springer
Abstract Obesity and Metabolic Syndrome have been associated with cardiovascular,
diabetes and cancer incidence. Obesity is a state of inflammation. There are cross-talks …

Evaluation of miRNA-21-5p and miRNA-10b-5p levels in serum-derived exosomes of breast cancer patients in different grades

A Asadirad, A Khodadadi, A Talaiezadeh… - Molecular and cellular …, 2022 - Elsevier
Background & objectives Tumor cells have various effects and dominance over other
healthy cells. Cancer cells alter the cell program in healthy cells by secreting exosomes …

[HTML][HTML] MicroRNA expression in pre-treatment plasma of patients with benign breast diseases and breast cancer

M Lagendijk, S Sadaatmand, LB Koppert… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Background MicroRNAs (miRs) are small RNA molecules, influencing messenger RNA
(mRNA) expression and translation, and are readily detectable in blood. Some have been …

[HTML][HTML] Extracellular vesicles and their zeta potential as future markers associated with nutrition and molecular biomarkers in breast cancer

H Mendivil-Alvarado, AT Limon-Miro… - International Journal of …, 2023 - mdpi.com
A nutritional intervention promotes the loss of body and visceral fat while maintaining muscle
mass in breast cancer patients. Extracellular vesicles (EVs) and their characteristics can be …

[HTML][HTML] EV-miRNAs from breast cancer patients of plasma as potential prognostic biomarkers of disease recurrence

RL Causin, MR Polezi, AJA de Freitas, S Calfa… - Heliyon, 2024 - cell.com
Background Extracellular vesicles (EVs), ubiquitously released by blood cells, facilitate
intercellular communication. In cancer, tumor-derived EVs profoundly affect the …

[HTML][HTML] Role of microRNA regulation in obesity-associated breast cancer: nutritional perspectives

R Kasiappan, D Rajarajan - Advances in Nutrition, 2017 - Elsevier
Breast cancer is the most common malignancy diagnosed in women, and the incidence of
breast cancer is increasing every year. Obesity has been identified as one of the major risk …

[HTML][HTML] Identification of miRNAs enriched in extracellular vesicles derived from serum samples of breast cancer patients

PMM Ozawa, E Vieira, DS Lemos, ILM Souza… - Biomolecules, 2020 - mdpi.com
MicroRNAs derived from extracellular vesicles (EV-miRNAs) are circulating miRNAs
considered as potential new diagnostic markers for cancer that can be easily detected in …