Prior preclinical and clinical studies support the use of platelet-derived products for the
treatment of soft and hard tissue lesions. These regenerative effects are controlled by …

The preponderance of evidence indicates that platelets and their derivatives have the
potential for a substantial therapeutic role in tissue regeneration. The results of recent …

Orthobiologics continue to gain popularity in many areas of medical science, especially in
the field of regenerative medicine. Platelet-rich plasma derivatives are orthobiologic tools of …

The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …

Several biomaterials can be obtained from human blood. Some are used for clinical
indications requiring a high content in fibrinogen, while others are used because they …

Platelet derived bio-products in the form of platelet rich plasma, plasma rich in growth
factors, or plasma-free platelet releasates, are being studied worldwide with the aim of …

Numerous studies have explored the suitability of biocompatible materials in regenerative
medicine. Platelet concentrates are derived from centrifuged blood and are named …

BACKGROUND: In loco administration of platelet (PLT) derivatives is a relatively new
auxiliary treatment for tissue regeneration to be hastened. Enthusiastic reports are faced by …

Although platelets are widely recognized as having a critical role in primary hemostasis and
thrombosis, increasing experimental and clinical evidence identifies these enucleated cells …

Platelet degranulation allows the release of a large amount of soluble mediators, is an
essential step for wound healing initiation, and stimulates clotting, and angiogenesis. The …