[HTML][HTML] LncRNA HOTAIR promotes MPP+-induced neuronal injury in Parkinson's disease by regulating the miR-874-5p/ATG10 axis

J Zhao, H Li, N Chang - EXCLI journal, 2020 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a neurodegenerative disease caused by the loss of
dopaminergic neurons. Long non-coding RNAs (lncRNAs) play an important role in many …

LncRNA HOTAIR promotes α-synuclein aggregation and apoptosis of SH-SY5Y cells by regulating miR-221-3p in Parkinson's disease

Q Sun, Y Zhang, S Wang, F Yang, H Cai, Y Xing… - Experimental Cell …, 2022 - Elsevier
Parkinson's disease (PD) is a common neurodegenerative disease. Here, the purpose of the
study was to explore the function of long non-coding RNA (lncRNA) HOX transcript …

LncRNA HOTAIR promotes neuronal damage through facilitating NLRP3 mediated-pyroptosis activation in Parkinson's disease via regulation of miR-326/ELAVL1 …

Q Zhang, XM Huang, JX Liao, YK Dong, JL Zhu… - Cellular and Molecular …, 2021 - Springer
Parkinson's disease (PD) seriously threatens human's health. Researches have shown a
close correlation between long non-coding RNAs (lncRNAs) and PD. However, the …

[HTML][HTML] The long noncoding RNA HOTAIR promotes Parkinson's disease by upregulating LRRK2 expression

S Wang, X Zhang, Y Guo, H Rong, T Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) have emerged recently as a new class of genes that
regulate cellular processes. HOTAIR (Hox transcript antisense intergenic RNA), an …

LncRNA HOTAIR targets miR-126-5p to promote the progression of Parkinson's disease through RAB3IP

Q Lin, S Hou, Y Dai, N Jiang, Y Lin - Biological chemistry, 2019 - degruyter.com
Parkinson's disease (PD) is a common neurological disorder characterized by dopaminergic
(DA) neuron degeneration and death in the midbrain, and the long noncoding RNA HOTAIR …

Long non-coding RNA HOTAIR promotes Parkinson's disease induced by MPTP through up-regulating the expression of LRRK2

S Liu, B Cui, Z Dai, P Shi, Z Wang… - Current neurovascular …, 2016 - ingentaconnect.com
Homeobox (HOX) transcript antisense RNA (HOTAIR), as a long intergenic noncoding RNA
(lincRNA), is known to be overexpressed in several cancers. However, the role of HOTAIR in …

Dysregulated long non-coding RNAs in Parkinson's disease contribute to the apoptosis of human neuroblastoma cells

Y Fan, J Li, Q Yang, C Gong, H Gao, Z Mao… - Frontiers in …, 2019 - frontiersin.org
The molecular mechanism underlying Parkinson's disease (PD), an increasingly common
neurodegenerative disease, remains unclear. Long non-coding RNA (lncRNA) plays …

Knockdown of long non-coding RNA AL049437 mitigates MPP+-induced neuronal injury in SH-SY5Y cells via the microRNA-205-5p/MAPK1 axis

L Zhang, J Wang, Q Liu, Z Xiao, Q Dai - Neurotoxicology, 2020 - Elsevier
Abstract Background Long noncoding RNAs (lncRNAs) have been defined as critical
regulators of various human diseases. However, the functions of lncRNAs in Parkinson's …

LncRNA H19 attenuates apoptosis in MPTP-induced Parkinson's disease through regulating miR-585-3p/PIK3R3

Y Zhang, Q Xia, J Lin - Neurochemical research, 2020 - Springer
Parkinson's disease (PD) is a prevalent age-related neurodegenerative disease which is
modulated by various molecules, including long non-coding RNAs (lncRNAs). LncRNA H19 …

LINC00943 knockdown attenuates MPP+-induced neuronal damage via miR-15b-5p/RAB3IP axis in SK-N-SH cells

C Meng, J Gao, Q Ma, Q Sun, T Qiao - Neurological Research, 2021 - Taylor & Francis
Objectives Parkinson's disease (PD) is a neurodegenerative problem correlated with
neuronal damage. Long noncoding RNAs (lncRNAs) are implicated in neuronal damage in …