A Comprehensive Analysis of the Impact of Pseudomonas aeruginosa Colonization on Prognosis in Adult Bronchiectasis

S Finch, MJ McDonnell, H Abo-Leyah… - Annals of the …, 2015 - atsjournals.org
Rationale: Eradication and suppression of Pseudomonas aeruginosa is a key priority in
national guidelines for bronchiectasis and is a major focus of drug development and clinical …

The independent contribution of Pseudomonas aeruginosa infection to long-term clinical outcomes in bronchiectasis

D Araújo, M Shteinberg, S Aliberti… - European …, 2018 - Eur Respiratory Soc
Pseudomonas aeruginosa is responsible for chronic infection in many bronchiectasis
patients but it is not known whether it is associated with worse clinical outcomes …

Pseudomonas aeruginosa in bronchiectasis: infection, inflammation, and therapies

C Vidaillac, SH Chotirmall - Expert review of respiratory medicine, 2021 - Taylor & Francis
Introduction: Bronchiectasis is a chronic endobronchial suppurative disease characterized
by irreversibly dilated bronchi damaged by repeated polymicrobial infections and …

The effect of Pseudomonas aeruginosa on pulmonary function in patients with bronchiectasis

G Davies, AU Wells, S Doffman… - European …, 2006 - Eur Respiratory Soc
Bronchiectasis patients are susceptible to infection with Pseudomonas aeruginosa. Isolation
is associated with increased severity of disease, greater airflow obstruction and poorer …

[HTML][HTML] Challenges in managing Pseudomonas aeruginosa in non-cystic fibrosis bronchiectasis

R Wilson, T Aksamit, S Aliberti, A De Soyza… - Respiratory …, 2016 - Elsevier
Abstract Background An Expert Forum was held at the 2014 European Respiratory Society
International Congress to address issues involved in the management of Pseudomonas …

[HTML][HTML] Pseudomonas aeruginosa and lung function decline in patients with bronchiectasis

MA Martinez-García, G Oscullo, T Posadas… - Clinical Microbiology …, 2021 - Elsevier
Objectives The objective of this study was to analyse lung function decline over time in
bronchiectasis, along with the factors associated with it. Methods Spirometry was measured …

[HTML][HTML] Outcomes of Pseudomonas eradication therapy in patients with non-cystic fibrosis bronchiectasis

L White, G Mirrani, M Grover, J Rollason, A Malin… - Respiratory …, 2012 - Elsevier
Pseudomonas aeruginosa infection is associated with poorer outcomes in non-cystic fibrosis
bronchiectasis. It is unknown whether early eradication improves outcomes. This …

[HTML][HTML] Non cystic fibrosis bronchiectasis: A longitudinal retrospective observational cohort study of Pseudomonas persistence and resistance

MJ McDonnell, HR Jary, A Perry, JG MacFarlane… - Respiratory …, 2015 - Elsevier
Background The hallmark of non-cystic fibrosis bronchiectasis is recurrent bronchial
infection, yet there are significant gaps in our understanding of pathogen persistence …

Addition of inhaled tobramycin to ciprofloxacin for acute exacerbations of Pseudomonas aeruginosa infection in adult bronchiectasis

D Bilton, N Henig, B Morrissey, M Gotfried - Chest, 2006 - Elsevier
Rationale: Pseudomonas aeruginosa lung infection in patients with bronchiectasis, a
chronic airway disease that is characterized by episodes of exacerbation, is associated with …

The economic burden of bronchiectasis–known and unknown: a systematic review

PC Goeminne, F Hernandez, R Diel, A Filonenko… - BMC pulmonary …, 2019 - Springer
Background The increasing prevalence and recognition of bronchiectasis in clinical practice
necessitates a better understanding of the economic disease burden to improve the …