Background Aging is one factor believed to contribute to processes that underlie chronic low-
grade inflammation in older adults. Moreover, more recent studies have suggested that …

Objective. To determine the association among aging, inflammation, and cytokine
production by peripheral blood mononuclear cells. Population and Methods. We examined …

PURPOSE: To review findings from major epidemiologic studies regarding risk factors for
and consequences of elevated markers of inflammation in older adults. RESULTS: Most …

Background. Inflammation plays a major role in both aging and chronic disease.
Longitudinal studies in very old people can improve our understanding of these processes …

We examined the serum levels of IL-6, IL-8, TNF, IL-6R, TNF-R1, and CRP and the dynamics
of changes in these levels according to age. The study included healthy individuals of 20–90 …

PURPOSE: Aging is accompanied by a progressive increase in pro-inflammatory cytokine
status. However, little is known about the development of age-dependent modifications in …

Systemic inflammation is associated with increasing age. Yet, there are limited data about
the association between age and systemic inflammation within older adults, and whether …

Ageing is associated with low-grade inflammation and markers such as IL-6 possess
prognostic value. Tumour necrosis-alpha (TNF-α) initiates the inflammatory cascade and …

It is known that as we age, immune dysregulation often occurs, leading to failing health, and
increased susceptibility to a number of different diseases. In this study we have investigated …

OBJECTIVES: To investigate whether interleukin‐6 (IL‐6), C‐reactive protein (CRP) and
tumor necrosis factor‐alpha (TNF‐α) protein levels predict all‐cause mortality in older …