Viral infections are known to hijack the transcription and translation of the host cell.
However, the extent to which viral proteins coordinate these perturbations remains unclear …

Adult T-cell leukemia/lymphoma (ATL) is a T-cell lymphoproliferative neoplasm caused by
the human T-cell leukemia virus type 1 (HTLV-1). Two viral proteins, Tax-1 and HBZ play …

Human T-lymphotropic virus type 1 (HTLV-1) encodes the viral protein Tax, which is
believed to act as a viral transactivator through its interactions with a variety of transcription …

Abstract The Really Interesting New Gene (RING) Finger Protein 4 (RNF4) represents a
class of ubiquitin ligases that target Small Ubiquitin-like Modifier (SUMO)–modified proteins …

Human T-cell leukemia virus type 1 (HTLV-1), the first reported human oncogenic retrovirus,
is the etiologic agent of highly aggressive, currently incurable diseases such as adult T-cell …

Alternative splicing (AS) is a widespread process that increases structural transcript variation
and proteome diversity. Aberrant splicing patterns are frequently observed in cancer …

Viruses disrupt the host cell microRNA (miRNA) network to facilitate their replication. Human
T-cell leukemia virus type I (HTLV-1) replication relies on the clonal expansion of its host …

Alternative splicing (AS) is a central mechanism of genetic regulation which modifies the
sequence of RNA transcripts in higher eukaryotes. AS has been shown to increase both the …

Human T-cell leukemia virus (HTLV) infection is a chronic, lifelong infection that is
associated with the development of leukemia and neurological disease after a long latency …

HTLV-1 (Human T-cell lymphotropic virus type 1) is a complex human delta retrovirus that
currently infects 10–20 million people worldwide. While HTLV-1 infection is generally …