By general consensus, the omnipresent purine nucleoside adenosine is considered a major
regulator of local tissue function, especially when energy supply fails to meet cellular energy …

Adenosine is a primordial signaling molecule present in every cell of the human body that
mediates its physiological functions by interacting with 4 subtypes of G-protein-coupled …

Background: Adenosine is an endogenous purine nucleoside, which mediates a variety of
important biological processes and diseases, such as vasodilation, inflammation, cancer …

A3 Adenosine receptors (ARs) exhibit large species differences. Potent, selective agonists
for rat (eg Cl-IB-MECA, 5) and human A3 ARs (eg PENECA, 17, and analogs) have been …

Adenosine A1 and A2 receptors have been the subject of intense activity in the
pharmaceutical industry. Adenosine agonists, which are almost exclusively derivatives of …

Adenosine's diverse physiological functions are mediated by four subtypes of receptors (A1,
A2A, A2B and A3). The A1 adenosine receptor pharmacology and therapeutic application of …

Extracellular adenosine binds specifically to a family of four G protein-coupled cell-surface
adenosine receptors (ARs). As the activation of the A2AAR modulates the activity of multiple …

The adenosine receptors A 1, A 2A, A 2B, and A 3 are important and ubiquitous mediators of
cellular signaling, which play vital roles in protecting tissues and organs from damage. In …

Adenosine receptors (ARs) are a four-member subfamily of G protein-coupled receptors and
are major targets of caffeine and theophylline. There are four subtypes of ARs, designated …

Adenosine receptors belong to the family of G protein-coupled receptors. Four distinct
subtypes are known, termed A1, A2A, A2B and A3. Adenosine is an important signaling …