Background DNA methylation-regulated genes have been demonstrated as the crucial
participants in the occurrence of coronary heart disease (CHD). The machine learning …

DNA methylation plays an essential role in the pathogenesis of coronary artery disease
(CAD) through regulating mRNA expressions. This study aimed to identify hub genes …

Background: Identifying environmentally responsive genetic loci where DNA methylation is
associated with coronary heart disease (CHD) may reveal novel pathways or therapeutic …

Coronary heart disease (CHD) is a type of cardiovascular disease (CVD) that affects the
coronary arteries, which provide oxygenated blood to the heart. It is a major cause of …

Background To better understand the molecular mechanisms of atherosclerosis, we
conducted a comparative analysis of DNA methylation patterns in right coronary arteries in …

Background Gene environment interactions leading to epigenetic alterations play pivotal
role in the pathogenesis of Coronary Artery Disease (CAD). Altered DNA methylation is one …

To evaluate DNA methylation sites and gene expression associated with coronary artery
disease (CAD) and the possible pathological mechanism involved, we performed (1) …

Background The alteration in the epigenome forms an interface between the genotype and
the environment. Epigenetic alteration is expected to make a significant contribution to the …

Background and aims The aim of this study was to perform a systematic review of the
association between DNA methylation and coronary heart disease (CHD) or related …

Epidemiological studies have revealed that coronary artery disease (CAD) is highly
heritable. However, genetic studies have not been able to fully elucidate its etiology …