T helper-17 (Th17) cells, which mainly produce IL-17, are associated with development of
various autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases …

In this review, we summarize the current knowledge of IL-17 and Th17 cells and discuss the
possible role of IL-17 in the pathology of psoriasis, contact hypersensitivity and atopic …

The critical role of IL-17 has recently been reported in a variety of conditions. Since IL-17
deeply participates in the pathogenesis of psoriasis and keratinocyte production of certain …

Abstract The classical Th1/Th2 paradigm previously defining atopic dermatitis (AD) and
psoriasis has recently been challenged with the discovery of Th17 T cells that synthesize IL …

BACKGROUND: Psoriasis and atopic dermatitis (AD) are common inflammatory skin
diseases. An upregulated TH17/IL-23 pathway was demonstrated in psoriasis. Although …

The role of T cell subpopulations in human disease is in a transition phase due to
continuous discovery of new subsets of T cell, one of which is Th17, characterized by the …

Atopic dermatitis (AD) is generally regarded as a type 2 helper T (Th2)-mediated
inflammatory skin disease. Although the number of IL-17A-producing cells is increased in …

Extending the classical concept considering an imbalance exclusively of T helper (h) 1 and
Th2 cells on the bottom of many inflammatory diseases, Th17 cells were recently described …

T helper (Th) 17 cells have crucial functions in host defense, and dysregulated Th17
responses mediate a variety of autoimmune and inflammatory conditions. Th17 cells …

BACKGROUND: IL-17–producing TH (TH17) cells are key mediators of chronic inflammation
in mice. Recent studies have implicated TH17-mediated inflammation in the pathogenesis of …