Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline

M Savitsky, D Kwon, P Georgiev… - Genes & …, 2006 - genesdev.cshlp.org
Telomeres in Drosophila are maintained by transposition of specialized telomeric
retroelements HeT-A, TAHRE, and TART instead of the short DNA repeats generated by …

Characterization of Drosophila Telomeric Retroelement TAHRE: Transcription, Transpositions, and RNAi-based Regulation of Expression

S Shpiz, D Kwon, A Uneva, M Kim… - Molecular biology …, 2007 - academic.oup.com
Telomeres in Drosophila are maintained by transpositions of specialized telomeric
retroelements HeT-A and TART rather than by the telomerase activity adding short DNA …

Silence at the end: How Drosophila regulates expression and transposition of telomeric retroelements

S Cacchione, G Cenci, GD Raffa - Journal of molecular biology, 2020 - Elsevier
The maintenance of chromosome ends in Drosophila is an exceptional phenomenon
because it relies on the transposition of specialized retrotransposons rather than on the …

Drosophila telomeres: an exception providing new insights

JM Mason, RC Frydrychova, H Biessmann - Bioessays, 2008 - Wiley Online Library
Drosophila telomeres comprise DNA sequences that differ dramatically from those of other
eukaryotes. Telomere functions, however, are similar to those found in telomerase‐based …

rasiRNA pathway controls antisense expression of Drosophila telomeric retrotransposons in the nucleus

S Shpiz, D Kwon, Y Rozovsky… - Nucleic acids …, 2009 - academic.oup.com
Telomeres in Drosophila are maintained by the specialized telomeric retrotransposons HeT-
A, TART and TAHRE. Sense transcripts of telomeric retroelements were shown to be the …

Drosophila telomeres: the non-telomerase alternative

L Melnikova, P Georgiev - Chromosome Research, 2005 - Springer
In most eukaryotes, telomeres are composed of simple repetitive sequences renewable by
telomerase. By contrast, Drosophila telomeres comprise arrays of non-LTR retrotransposons …

TAHRE, a Novel Telomeric Retrotransposon from Drosophila melanogaster, Reveals the Origin of Drosophila Telomeres

JP Abad, B De Pablos, K Osoegawa… - Molecular biology …, 2004 - academic.oup.com
Drosophila telomeres do not have typical telomerase repeats. Instead, two families of non-
LTR retrotransposons, HeT-A and TART, maintain telomere length by occasional …

Two retrotransposons maintain telomeres in Drosophila

ML Pardue, S Rashkova, E Casacuberta… - Chromosome …, 2005 - Springer
Telomeres across the genus Drosophila are maintained, not by telomerase, but by two non-
LTR retrotransposons, HeT-A and TART, that transpose specifically to chromosome ends …

Retrotransposons provide an evolutionarily robust non-telomerase mechanism to maintain telomeres

ML Pardue, PG DeBaryshe - Annual review of genetics, 2003 - annualreviews.org
▪ Abstract Telomere molecular biology is far more complex than originally thought.
Understanding biological systems is aided by study of evolutionary variants, and Drosophila …

Telomere protection without a telomerase: the role of ATM and Mre11 in Drosophila telomere maintenance

X Bi, SCD Wei, YS Rong - Current biology, 2004 - cell.com
The conserved ATM checkpoint kinase and the Mre11 DNA repair complex play essential
and overlapping roles in maintaining genomic integrity. We conducted genetic and …