Molecular mechanisms linking neuroinflammation and neurodegeneration in MS
E Ellwardt, F Zipp - Experimental neurology, 2014 - Elsevier
Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disorder of the central
nervous system (CNS) and one of the leading causes of neurological deficits and disability …
nervous system (CNS) and one of the leading causes of neurological deficits and disability …
Neurodegeneration in autoimmune CNS inflammation
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system, in which the myelin sheath has been considered to be the primary target for …
nervous system, in which the myelin sheath has been considered to be the primary target for …
What drives disease in multiple sclerosis: inflammation or neurodegeneration?
H Lassmann - Clinical and Experimental Neuroimmunology, 2010 - Wiley Online Library
Multiple sclerosis (MS) is defined as a chronic inflammatory disease of the central nervous
system, which leads to focal inflammatory demyelinated lesions with secondary …
system, which leads to focal inflammatory demyelinated lesions with secondary …
[HTML][HTML] The molecular basis of neurodegeneration in multiple sclerosis
H Lassmann, J van Horssen - FEBS letters, 2011 - Elsevier
Studies aimed to elucidate the pathogenesis of the disease and to find new therapeutic
options for multiple sclerosis (MS) patients heavily rely on experimental autoimmune …
options for multiple sclerosis (MS) patients heavily rely on experimental autoimmune …
Neuroinflammation, neurodegeneration and regeneration in multiple sclerosis: intercorrelated manifestations of the immune response
T Koudriavtseva, C Mainero - Neural regeneration research, 2016 - journals.lww.com
Multiple sclerosis (MS) is a chronic immune-mediated inflammatory-demyelinating disorder
of the central nervous system, with a strong neurodegenerative component. The question …
of the central nervous system, with a strong neurodegenerative component. The question …
The translatability of multiple sclerosis animal models for biomarkers discovery and their clinical use
D Birmpili, I Charmarke Askar, K Bigaut… - International journal of …, 2022 - mdpi.com
Multiple Sclerosis (MS) is a chronic autoimmune disease affecting the central nervous
system which is characterized by demyelinating lesions and axonal damage. MS is a …
system which is characterized by demyelinating lesions and axonal damage. MS is a …
Neurodegeneration in multiple sclerosis: novel treatment strategies
In recent years it has become clear that the neuronal compartment already plays an
important role early in the pathology of multiple sclerosis (MS). Neuronal injury in the course …
important role early in the pathology of multiple sclerosis (MS). Neuronal injury in the course …
Macrophages and neurodegeneration
JJA Hendriks, CE Teunissen, HE de Vries… - Brain Research …, 2005 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). Demyelination is a classical feature of MS lesions, and neurological …
nervous system (CNS). Demyelination is a classical feature of MS lesions, and neurological …
Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases
The central nervous system (CNS) is now known to actively communicate with the immune
system to control immune responses both centrally and peripherally. Within the CNS, while …
system to control immune responses both centrally and peripherally. Within the CNS, while …
Molecular pathogenesis of neuroinflammation
M Bradl, R Hohlfeld - Journal of Neurology, Neurosurgery & Psychiatry, 2003 - jnnp.bmj.com
The past few years have seen significant progress towards understanding the mechanisms
of immune surveillance and inflammation in the nervous system. In this review, the …
of immune surveillance and inflammation in the nervous system. In this review, the …