Penetrance of the complex of genes predisposing the nonobese diabetic (NOD) mouse to
autoimmune diabetes is affected by the maternal environment. NOD. CBALs-Tyr+/Lt is an …

It would be extremely advantageous to the analysis of disease mechanisms in the
spontaneous mouse model of type 1 diabetes, the nonobese diabetic (NOD) strain, if genes …

Recombinant Congenic Strains (RCS) are useful for dissecting complex polygenic traits.
Here, we describe genetic and phenotypic characterization of six new RCS generated from …

Nonobese diabetic (NOD) mice provide an excellent model of type 1 diabetes. The genetic
contribution to this disease is complex, with more than 20 loci implicated in diabetes onset …

Nonobese diabetic (NOD) mice spontaneously develop autoimmune T cell‐mediated insulin‐
dependent diabetes mellitus (IDDM). This unit presents a protocol for maintaining NOD mice …

The manipulation of a specific gene in NOD mice, the best animal model for insulin‐
dependent diabetes mellitus (IDDM), must allow for the precise characterization of the …

The nonobese diabetic (NOD) mouse is genetically predisposed for the spontaneous
development of type 1 diabetes. Linkage analyses have identified at least 19 susceptibility …

The NOD mouse has been a critical tool in the quest to understand the genetic control of
type 1 diabetes (T1D), and over 25 murine insulin-dependent diabetes (Idd) loci that …

Twenty-four named Idd loci that contribute to the development of autoimmune diabetes in
the nonobese diabetic (NOD) mouse have been mapped by linkage and congenic analysis …

Autoimmune diabetes is a polygenic disease process in man and rodents. To identify and
characterize genes involved in the pathogenesis of diabetes in nonobese diabetic (NOD) …