What's new in estrogen receptor action in the female reproductive tract

SC Hewitt, W Winuthayanon… - Journal of molecular …, 2016 - jme.bioscientifica.com
Significant progress has been made recently in unravelling the embryonic events leading to
pituitary morphogenesis, both in vivo and in vitro. This includes dissection of the molecular …

[HTML][HTML] Genetic regulation of murine pituitary development

K Rizzoti - Journal of molecular endocrinology, 2015 - ncbi.nlm.nih.gov
Significant progress has been made recently in unravelling the embryonic events leading to
pituitary morphogenesis, both in vivo and in vitro. This includes dissection of the molecular …

Pituitary stem cell regulation: who is pulling the strings?

B Cox, H Roose, A Vennekens… - Journal of …, 2017 - joe.bioscientifica.com
The pituitary gland plays a pivotal role in the endocrine system, steering fundamental
processes of growth, metabolism, reproduction and coping with stress. The adult pituitary …

Oestrogen receptors, receptor variants and oestrogen actions in the hypothalamic‐pituitary axis

MA Shupnik - Journal of neuroendocrinology, 2002 - Wiley Online Library
Abstract Information on oestrogen action has grown exponentially in the past decade, and
recent studies have begun to define the mechanism of ligand‐dependent activation and cell …

Estrogen receptors and signaling pathways in lactotropes and somatotropes

S Zárate, A Seilicovich - Neuroendocrinology, 2010 - karger.com
Estrogens are crucial determinants in the regulation of anterior pituitary function and
maintenance of tissue homeostasis. Estrogen actions in this gland are exerted through both …

Pituitary stem cells: where do we stand?

H Vankelecom, J Chen - Molecular and cellular endocrinology, 2014 - Elsevier
Some 5 years ago, the stem cells of the adult pituitary gland were discovered. Subsequent in-
depth characterization revealed expression of several stemness markers and embryo-typical …

Estrogen receptors: bioactivities and interactions with cell signaling pathways

BS Katzenellenbogen - Biology of reproduction, 1996 - academic.oup.com
Estrogens regulate the growth, differentiation, and functioning of diverse target tissues, both
within and outside of the reproductive system. Most of the actions of estrogens appear to be …

Pituitary remodeling throughout life: are resident stem cells involved?

E Laporte, A Vennekens, H Vankelecom - Frontiers in endocrinology, 2021 - frontiersin.org
The pituitary gland has the primordial ability to dynamically adapt its cell composition to
changing hormonal needs of the organism throughout life. During the first weeks after birth …

Pituitary gonadotroph estrogen receptor-α is necessary for fertility in females

MC Gieske, HJ Kim, SJ Legan, Y Koo, A Krust… - …, 2008 - academic.oup.com
Estrogens play a central role in regulating female reproduction throughout the reproductive
axis, and the pituitary is one of the major targets of estrogen action. We hypothesized that …

Pituitary gland development and disease: from stem cell to hormone production

SW Davis, BS Ellsworth, MIP Millan, P Gergics… - Current topics in …, 2013 - Elsevier
Many aspects of pituitary development have become better understood in the past two
decades. The signaling pathways regulating pituitary growth and shape have emerged, and …