Chalcones are interesting anticancer drug candidates which have attracted much interest
due to their unique structure and their extensive biological activity. Various functional …

Cancer treatment still requires new compounds to be discovered. Chalcone and its
derivatives exhibit anticancer potential in different cancer cells. A new series of benzofuran …

A Series of chalcone derivatives containing pyrazole ring was prepared and their cytotoxicity
against different human cell lines, including breast (MCF-7), colon (HCT-116) liver (HEPG2) …

Building on our previous work that discovered chalcone as a promising pharmacophore for
anticancer activity, we have various other chalcone derivatives and have synthesized a …

Chalcones are valuable structures for drug discovery due to their broad bioactivity spectrum.
In this study, we evaluated 20 synthetic chalcones against estrogen-receptor-positive breast …

Many natural or synthetic chalcones have potential anti-tumor activity. Here, we synthesized
two series of chalcone analogues containing a thieno [2, 3-d] pyrimidin-2-yl group and …

A double Claisen rearrangements synthetic strategy was established for the total synthesis
of 4, 4′-dimethyl medicagenin (compound 6c). A series of its analogs also were prepared …

Abstract Novel tetrahydro-[1, 2, 4] triazolo [3, 4-a] isoquinolin-3-yl)-3-arylprop-2-en-1-one
derivatives were synthesized and their structures were confirmed by different spectral tools …

Chalcone is a common simple fragment of natural products with anticancer activity. In a
previous study, the research group discovered a series of chalcone derivatives with stronger …

Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …