Positive correlation between interleukin-1 receptor antagonist gene 86bp VNTR polymorphism and colorectal cancer susceptibility: a case-control study

M Ibrahimi, M Moossavi, EN Mojarad, M Musavi… - Immunologic …, 2019 - Springer
Colorectal cancer (CRC) is one of the most common malignancies worldwide. Genetic
variations in cytokine genes and their receptors lead to the severity of the disease. The …

[PDF][PDF] Association of interleukin-1 gene polymorphism with risk of gastric and colorectal cancers in an Iranian population

MH Abbasian, B Abbasi, N Ansarinejad… - Iranian Journal of …, 2018 - iji.sums.ac.ir
Background: Chronic inflammation is associated with neoplasms and several types of
cancer. Therefore, polymorphisms in the inflammation-related genes could modify the …

[HTML][HTML] Risk modification of colorectal cancer susceptibility by interleukin-8-251T> A polymorphism in Malaysians

MA Mustapha, SNM Shahpudin, AAA Aziz… - World Journal of …, 2012 - ncbi.nlm.nih.gov
AIM: To investigate the allele and genotype frequencies and associated risk of interleukin
(IL)-8-251T> A polymorphism on colorectal cancer (CRC) susceptibility risk. METHODS …

Interleukin-1 receptor antagonist gene polymorphism in human colorectal cancer

HT Viet, D Wågsäter, A Hugander… - Oncology …, 2005 - spandidos-publications.com
Several studies indicate that local immunoregulation and associated cytokines have a
putative role in the development of cancer. There is evidence that pro-inflammatory …

Interleukin-1β (IL-1β)-31C/T and-511T/C promoter single nucleotide polymorphism in colorectal cancer in ethnic Kashmiri population-a case control study

MZ Banday, AH Mir, AS Sameer, NA Chowdri, E Haq - Meta Gene, 2017 - Elsevier
Background Chronic inflammation is a vital component of colorectal cancer pathogenesis.
Interleukin-1β (IL-1β) is one of the key regulators of GIT inflammatory homeostasis and plays …

Interleukin-1β, interleukin-6 and interleukin-10 polymorphisms in Tunisian patients with colorectal cancer and liver metastasis

M Hazgui, M Weslati, D Ounissi… - Archives of Biological …, 2022 - serbiosoc.org.rs
The balance between pro-and anti-inflammatory cytokine expression is essential for an
efficient immune response and for the regulation of cancer development and progression …

IL-1RN+ 2018T> C polymorphism is correlated with colorectal cancer

F Burada, T Dumitrescu, R Nicoli, ME Ciurea… - Molecular biology …, 2013 - Springer
Epidemiological and experimental evidence indicates chronic inflammation as a risk factor
for colorectal cancer. We investigated whether IL-1B− 511C> T (rs16944), IL-1B+ 3954C> T …

[HTML][HTML] Two variants of Interleukin-1B gene are associated with the decreased risk, clinical features, and better overall survival of colorectal cancer: a two-center case …

H Qian, D Zhang, C Bao - Aging (Albany NY), 2018 - ncbi.nlm.nih.gov
Abstract Interleukin (IL)-1B reportedly promotes the stemness and invasiveness of colon
cancer cells. Several studies have investigated the association between IL-1B gene …

Interleukin-1 receptor antagonist VNTR-polymorphism in inflammatory bowel disease

L Vijgen, M Van Gysel, A Rector, I Thoelen, N Esters… - Genes & …, 2002 - nature.com
Both genetic and environmental factors have been implicated in the etiology of inflammatory
bowel diseases (IBD) ie, Crohn's disease (CD) and ulcerative colitis (UC). Polymorphisms in …

[HTML][HTML] A preliminary study of cytokine gene polymorphism effects on Saudi patients with colorectal cancer

SA Althubyani, AF Alkhuriji, SY Al Omar… - Saudi medical …, 2020 - ncbi.nlm.nih.gov
Objectives: To determine the possible associations of polymorphisms in interleukin (IL)-8
(rs4073 T/A), IL-10 (rs1800896 A/G), IL-22 (rs1179251 C/G and rs2227485 C/T), IL-27 …